9kmz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Bat MERSr-CoV NL140422 Nsp1 bound to the Human 40S Ribosomal subunit-State1== | |
| - | + | <StructureSection load='9kmz' size='340' side='right'caption='[[9kmz]], [[Resolution|resolution]] 2.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9kmz]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KMZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KMZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.78Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kmz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kmz OCA], [https://pdbe.org/9kmz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kmz RCSB], [https://www.ebi.ac.uk/pdbsum/9kmz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kmz ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RSSA_HUMAN RSSA_HUMAN] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.<ref>PMID:6300843</ref> <ref>PMID:16263087</ref> <ref>PMID:15516338</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wu M]] | ||
| + | [[Category: Yan R]] | ||
| + | [[Category: Yuan S]] | ||
Current revision
Bat MERSr-CoV NL140422 Nsp1 bound to the Human 40S Ribosomal subunit-State1
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Categories: Homo sapiens | Large Structures | Wu M | Yan R | Yuan S
