8s6b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM structure of Apo form of catalytic domain of human HMG-CoA reductase== | |
| - | + | <StructureSection load='8s6b' size='340' side='right'caption='[[8s6b]], [[Resolution|resolution]] 2.06Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8s6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8S6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8S6B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.06Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8s6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8s6b OCA], [https://pdbe.org/8s6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8s6b RCSB], [https://www.ebi.ac.uk/pdbsum/8s6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8s6b ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HMDH_HUMAN HMDH_HUMAN] Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Manikandan K]] | ||
| + | [[Category: Van Rooyen J]] | ||
Current revision
CryoEM structure of Apo form of catalytic domain of human HMG-CoA reductase
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