9jum
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Structure of Arabidopsis thaliana ABCB1 with brassinolide and AMP-PNP bound in the inward-facing conformation== | |
- | + | <StructureSection load='9jum' size='340' side='right'caption='[[9jum]], [[Resolution|resolution]] 3.10Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9jum]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JUM FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=BLD:BRASSINOLIDE'>BLD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jum OCA], [https://pdbe.org/9jum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jum RCSB], [https://www.ebi.ac.uk/pdbsum/9jum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jum ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/AB1B_ARATH AB1B_ARATH] Auxin efflux transporter that acts as a negative regulator of light signaling to promote hypocotyl elongation. Mediates the accumulation of chlorophyll and anthocyanin, as well as the expression of genes in response to light. Participates directly in auxin efflux and thus regulates the polar (presumably basipetal) auxin transport (from root tips to root elongating zone). Transports also some auxin metabolites such as oxindoleacetic acid and indoleacetaldehyde. Involved in diverse auxin-mediated responses including gravitropism, phototropism and lateral root formation. Confers resistance to herbicides such as dicamba, pendimethalin, oryzalin, and monosodium acid methanearsonate (MSMA), but not to herbicides such as glyphosate, atrazine, bentazon and fluazifop-p-butyl. Mediates also resistance to xenobiotics such as cycloheximide and the cytokinin N6-(2-isopentenyl)adenine (2IP).<ref>PMID:10760241</ref> <ref>PMID:11701880</ref> <ref>PMID:12640467</ref> <ref>PMID:14517332</ref> <ref>PMID:15908594</ref> <ref>PMID:16212599</ref> <ref>PMID:9761790</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Arabidopsis thaliana]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Chen Q]] |
Current revision
Structure of Arabidopsis thaliana ABCB1 with brassinolide and AMP-PNP bound in the inward-facing conformation
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