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9ktb

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(New page: '''Unreleased structure''' The entry 9ktb is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures)
Current revision (08:06, 11 December 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9ktb is ON HOLD until Paper Publication
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==Bacillus subtilis CpfC (HemH) Y13C variant modified with bromobimane==
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<StructureSection load='9ktb' size='340' side='right'caption='[[9ktb]], [[Resolution|resolution]] 1.13&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9ktb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KTB FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.13&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9UM:3-(bromomethyl)-2,5,6-trimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione'>9UM</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ktb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ktb OCA], [https://pdbe.org/9ktb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ktb RCSB], [https://www.ebi.ac.uk/pdbsum/9ktb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ktb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPFC_BACSU CPFC_BACSU] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:25646457, PubMed:25908396). It can also insert iron into protoporphyrin IX (PubMed:1459957, PubMed:21052751, PubMed:25646457, PubMed:8119288). Has weaker activity with 2,4 disulfonate, deuteroporphyrin and 2,4 hydroxyethyl (PubMed:12761666, PubMed:25646457). In vitro, can also use Zn(2+) or Cu(2+) (PubMed:12761666, PubMed:16140324, PubMed:21052751, PubMed:8119288).<ref>PMID:12761666</ref> <ref>PMID:1459957</ref> <ref>PMID:16140324</ref> <ref>PMID:21052751</ref> <ref>PMID:25646457</ref> <ref>PMID:25826316</ref> <ref>PMID:25908396</ref> <ref>PMID:8119288</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Large Structures]]
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[[Category: Fujishiro T]]
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[[Category: Shishido M]]

Current revision

Bacillus subtilis CpfC (HemH) Y13C variant modified with bromobimane

PDB ID 9ktb

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