Proteopedia:Featured EDU/9

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Image:2vv5-2oau-morf-mechanosensitive-channel.gif|center
Image:2vv5-2oau-morf-mechanosensitive-channel.gif|center
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default [[Drug and peptide transport in humans]]
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default [[Mechanosensitive channels: opening and closing]]
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<tr><td><div class="scrolling">'''You Are What You Eat!'''<br>
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<tr><td><div class="scrolling">'''Touch-Sensitive Channel'''<br>
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Above is an integral membrane protein that takes up, into your intestinal cells, orally consumed peptide nutrients and drugs.
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Touching stretches cell membranes, opening mechanosensitive ion channels, leading to sensation by the nervous system.
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Its lumen-face (top) opens and binds
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Pictured is the transmembrane region of a similar channel in bacteria. When closed, the narrow opening is lined by hydrophobic
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peptide or drug (small solid object in the center),
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amino acid sidechains, making it non-conductive to ions.
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then closes, while its cytoplasmic face (bottom) opens to release its cargo
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into the intestinal cell, which passes it on to the blood circulation.
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>>> [[Drug and peptide transport in humans|See more animations and explanation]] >>>
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>>> [[Mechanosensitive channels: opening and closing|See more animations and explanation]] >>>
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Current revision

About this image
Touch-Sensitive Channel

Touching stretches cell membranes, opening mechanosensitive ion channels, leading to sensation by the nervous system. Pictured is the transmembrane region of a similar channel in bacteria. When closed, the narrow opening is lined by hydrophobic amino acid sidechains, making it non-conductive to ions.

>>> See more animations and explanation >>>

Proteopedia Page Contributors and Editors (what is this?)

Eric Martz

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