9c9z

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Current revision (06:35, 16 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9c9z is ON HOLD until Paper Publication
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==S.c INO80 in complex with Xenopus 0/80 nucleosome, INO80 Core==
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<StructureSection load='9c9z' size='340' side='right'caption='[[9c9z]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9c9z]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9C9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9C9Z FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9c9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9c9z OCA], [https://pdbe.org/9c9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9c9z RCSB], [https://www.ebi.ac.uk/pdbsum/9c9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9c9z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/INO80_YEAST INO80_YEAST] ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (PubMed:10952318, PubMed:12887900). Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates (PubMed:10952318, PubMed:10361278). The INO80 complex is involved in DNA repair by associating with 'Ser-129' phosphorylated H2A histones as a response to DNA damage (PubMed:15607974, PubMed:15607975).<ref>PMID:10361278</ref> <ref>PMID:10952318</ref> <ref>PMID:12887900</ref> <ref>PMID:15607974</ref> <ref>PMID:15607975</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Cheng YF]]
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[[Category: Kaur U]]
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[[Category: Narlikar GJ]]
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[[Category: Wu H]]

Current revision

S.c INO80 in complex with Xenopus 0/80 nucleosome, INO80 Core

PDB ID 9c9z

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