9hmx

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Current revision (05:39, 30 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9hmx is ON HOLD until Paper Publication
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==Structure of SteB-RipA complex from Mycobacterium tuberculosis==
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<StructureSection load='9hmx' size='340' side='right'caption='[[9hmx]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
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Authors: Carloni, G., Wehenkel, A.M., Alzari, P.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9hmx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HMX FirstGlance]. <br>
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Description: Structure of SteB-RipA complex from Mycobacterium tuberculosis
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
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[[Category: Carloni, G]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hmx OCA], [https://pdbe.org/9hmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hmx RCSB], [https://www.ebi.ac.uk/pdbsum/9hmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hmx ProSAT]</span></td></tr>
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[[Category: Wehenkel, A.M]]
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</table>
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[[Category: Alzari, P.M]]
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== Function ==
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[https://www.uniprot.org/uniprot/RIPA_MYCTU RIPA_MYCTU] Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.<ref>PMID:16495549</ref> <ref>PMID:17919286</ref> <ref>PMID:18463693</ref> <ref>PMID:20826344</ref> <ref>PMID:21864539</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Alzari PM]]
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[[Category: Carloni G]]
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[[Category: Wehenkel AM]]

Current revision

Structure of SteB-RipA complex from Mycobacterium tuberculosis

PDB ID 9hmx

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