9hvi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:53, 16 July 2025) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 9hvi is ON HOLD until Paper Publication
+
==PSMA in complex with nanobody 8==
-
 
+
<StructureSection load='9hvi' size='340' side='right'caption='[[9hvi]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
-
Authors: Alon, G., Zalk, R., Huynh, T.T., Zalutsky, M.R., Weizmann, Y., Zarivach, R., Papo, N.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[9hvi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HVI FirstGlance]. <br>
-
Description: PSMA in complex with nanobody 8
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.46&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
[[Category: Huynh, T.T]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hvi OCA], [https://pdbe.org/9hvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hvi RCSB], [https://www.ebi.ac.uk/pdbsum/9hvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hvi ProSAT]</span></td></tr>
-
[[Category: Zarivach, R]]
+
</table>
-
[[Category: Zalk, R]]
+
== Function ==
-
[[Category: Weizmann, Y]]
+
[https://www.uniprot.org/uniprot/FOLH1_HUMAN FOLH1_HUMAN] Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
-
[[Category: Zalutsky, M.R]]
+
__TOC__
-
[[Category: Papo, N]]
+
</StructureSection>
-
[[Category: Alon, G]]
+
[[Category: Camelus dromedarius]]
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Alon G]]
 +
[[Category: Huynh TT]]
 +
[[Category: Papo N]]
 +
[[Category: Weizmann Y]]
 +
[[Category: Zalk R]]
 +
[[Category: Zalutsky MR]]
 +
[[Category: Zarivach R]]

Current revision

PSMA in complex with nanobody 8

PDB ID 9hvi

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/9hvi"
Personal tools