9k20
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Cryo-EM structure of ATP-bound P2Y purinoceptor 2-miniGo-scFv16 complex== | |
- | + | <StructureSection load='9k20' size='340' side='right'caption='[[9k20]], [[Resolution|resolution]] 2.65Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9k20]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9K20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9K20 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.65Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9k20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9k20 OCA], [https://pdbe.org/9k20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9k20 RCSB], [https://www.ebi.ac.uk/pdbsum/9k20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9k20 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/P2RY2_HUMAN P2RY2_HUMAN] Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Mus musculus]] | ||
+ | [[Category: Lan B]] | ||
+ | [[Category: Lin B]] | ||
+ | [[Category: Liu X]] | ||
+ | [[Category: Zhang S]] |
Current revision
Cryo-EM structure of ATP-bound P2Y purinoceptor 2-miniGo-scFv16 complex
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Categories: Homo sapiens | Large Structures | Mus musculus | Lan B | Lin B | Liu X | Zhang S