9hz5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity== | |
| - | + | <StructureSection load='9hz5' size='340' side='right'caption='[[9hz5]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9hz5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HZ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HZ5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1A2B:4-[[(3~{S})-9-(cyclohexylmethyl)-5-[(3~{R},5~{R})-4-(3-fluoranyl-5-methoxy-phenyl)-3,5-dimethyl-piperazin-1-yl]sulfonyl-3-methyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{N},~{N}-dimethyl-aniline'>A1A2B</scene></td></tr> |
| - | [[Category: Paavilainen | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hz5 OCA], [https://pdbe.org/9hz5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hz5 RCSB], [https://www.ebi.ac.uk/pdbsum/9hz5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hz5 ProSAT]</span></td></tr> |
| - | [[Category: Shahid | + | </table> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ovis aries]] | ||
| + | [[Category: Paavilainen VO]] | ||
| + | [[Category: Shahid R]] | ||
Current revision
Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
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