9atv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==X-ray co-crystal structure of NCGC00685960 / NCATS-SM9335 in NNMT== | |
| - | + | <StructureSection load='9atv' size='340' side='right'caption='[[9atv]], [[Resolution|resolution]] 2.41Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9atv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ATV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ATV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.413Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AF6:8-[3-[(3~{S})-1-(2-cyclohexylethyl)piperidin-3-yl]-5-oxidanylidene-4~{H}-1,2,4-triazol-1-yl]-1~{H}-quinolin-2-one'>A1AF6</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9atv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9atv OCA], [https://pdbe.org/9atv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9atv RCSB], [https://www.ebi.ac.uk/pdbsum/9atv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9atv ProSAT]</span></td></tr> |
| - | [[Category: Olland | + | </table> |
| - | [[Category: White | + | == Function == |
| + | [https://www.uniprot.org/uniprot/NNMT_HUMAN NNMT_HUMAN] Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Olland A]] | ||
| + | [[Category: Suto R]] | ||
| + | [[Category: White A]] | ||
Current revision
X-ray co-crystal structure of NCGC00685960 / NCATS-SM9335 in NNMT
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