9i0m
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) saturating ATP+IMP-bound form, extended== | |
| - | + | <StructureSection load='9i0m' size='340' side='right'caption='[[9i0m]], [[Resolution|resolution]] 3.01Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9i0m]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9I0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9I0M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.01Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9i0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9i0m OCA], [https://pdbe.org/9i0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9i0m RCSB], [https://www.ebi.ac.uk/pdbsum/9i0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9i0m ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0QSU3_MYCS2 A0QSU3_MYCS2] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycolicibacterium smegmatis MC2 155]] | ||
| + | [[Category: Bulvas O]] | ||
| + | [[Category: Kouba T]] | ||
| + | [[Category: Pichova I]] | ||
Current revision
Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) saturating ATP+IMP-bound form, extended
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