1v75

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[[Image:1v75.gif|left|200px]]
 
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==Crystal structure of hemoglobin D from the Aldabra giant tortoise (Geochelone gigantea) at 2.0 A resolution==
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The line below this paragraph, containing "STRUCTURE_1v75", creates the "Structure Box" on the page.
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<StructureSection load='1v75' size='340' side='right'caption='[[1v75]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1v75]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aldabrachelys_gigantea Aldabrachelys gigantea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V75 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_1v75| PDB=1v75 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v75 OCA], [https://pdbe.org/1v75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v75 RCSB], [https://www.ebi.ac.uk/pdbsum/1v75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v75 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HBAD_ALDGI HBAD_ALDGI] Involved in oxygen transport from the lung to the various peripheral tissues.[UniProtKB:P07417]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v7/1v75_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v75 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Hemoglobin D (Hb D) from the Aldabra giant tortoise, Geochelone gigantea, was crystallized by the hanging drop vapor diffusion technique with a precipitant solution containing 10% polyethylene glycol 3350 and 50 mM HEPES-Na, pH 7.5. The Hb D crystals of G. gigantea, which diffract to at least a 2.0 A resolution, belong to the monoclinic space group C2 with unit cell dimensions of a = 112.1 A, b = 62.4 A, c = 54.0 A, and beta = 110.3 degrees. One alphabeta dimer molecule of Hb D existed in an asymmetric unit, with a calculated value of Vm of 2.77 A(3)Da(-1).
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'''Crystal structure of hemoglobin D from the Aldabra giant tortoise (Geochelone gigantea) at 2.0 A resolution'''
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Crystallization and preliminary X-ray diffraction study of hemoglobin D from the Aldabra giant tortoise, Geochelone gigantea.,Kuwada T, Hasegawa T, Satoh I, Ishikawa K, Shishikura F Protein Pept Lett. 2003 Aug;10(4):422-5. PMID:14529497<ref>PMID:14529497</ref>
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==Overview==
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Hemoglobin D (Hb D) from the Aldabra giant tortoise, Geochelone gigantea, was crystallized by the hanging drop vapor diffusion technique with a precipitant solution containing 10% polyethylene glycol 3350 and 50 mM HEPES-Na, pH 7.5. The Hb D crystals of G. gigantea, which diffract to at least a 2.0 A resolution, belong to the monoclinic space group C2 with unit cell dimensions of a = 112.1 A, b = 62.4 A, c = 54.0 A, and beta = 110.3 degrees. One alphabeta dimer molecule of Hb D existed in an asymmetric unit, with a calculated value of Vm of 2.77 A(3)Da(-1).
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==About this Structure==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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1V75 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Dipsochelys_dussumieri Dipsochelys dussumieri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V75 OCA].
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</div>
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<div class="pdbe-citations 1v75" style="background-color:#fffaf0;"></div>
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==Reference==
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==See Also==
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Crystallization and preliminary X-ray diffraction study of hemoglobin D from the Aldabra giant tortoise, Geochelone gigantea., Kuwada T, Hasegawa T, Satoh I, Ishikawa K, Shishikura F, Protein Pept Lett. 2003 Aug;10(4):422-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14529497 14529497]
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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[[Category: Dipsochelys dussumieri]]
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== References ==
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[[Category: Protein complex]]
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<references/>
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[[Category: Hasegawa, T.]]
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__TOC__
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[[Category: Ishikawa, K.]]
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</StructureSection>
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[[Category: Kuwada, T.]]
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[[Category: Aldabrachelys gigantea]]
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[[Category: Satoh, I.]]
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[[Category: Large Structures]]
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[[Category: Shishikura, F.]]
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[[Category: Hasegawa T]]
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[[Category: Geochelone gigantea]]
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[[Category: Ishikawa K]]
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[[Category: Hemoglobin d]]
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[[Category: Kuwada T]]
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[[Category: Reptilia]]
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[[Category: Satoh I]]
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[[Category: The aldabra giant tortoise]]
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[[Category: Shishikura F]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:10:17 2008''
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Current revision

Crystal structure of hemoglobin D from the Aldabra giant tortoise (Geochelone gigantea) at 2.0 A resolution

PDB ID 1v75

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