1v75
From Proteopedia
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- | [[Image:1v75.gif|left|200px]] | ||
- | < | + | ==Crystal structure of hemoglobin D from the Aldabra giant tortoise (Geochelone gigantea) at 2.0 A resolution== |
- | + | <StructureSection load='1v75' size='340' side='right'caption='[[1v75]], [[Resolution|resolution]] 2.02Å' scene=''> | |
- | You may | + | == Structural highlights == |
- | + | <table><tr><td colspan='2'>[[1v75]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aldabrachelys_gigantea Aldabrachelys gigantea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V75 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v75 OCA], [https://pdbe.org/1v75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v75 RCSB], [https://www.ebi.ac.uk/pdbsum/1v75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v75 ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/HBAD_ALDGI HBAD_ALDGI] Involved in oxygen transport from the lung to the various peripheral tissues.[UniProtKB:P07417] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v7/1v75_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v75 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | Hemoglobin D (Hb D) from the Aldabra giant tortoise, Geochelone gigantea, was crystallized by the hanging drop vapor diffusion technique with a precipitant solution containing 10% polyethylene glycol 3350 and 50 mM HEPES-Na, pH 7.5. The Hb D crystals of G. gigantea, which diffract to at least a 2.0 A resolution, belong to the monoclinic space group C2 with unit cell dimensions of a = 112.1 A, b = 62.4 A, c = 54.0 A, and beta = 110.3 degrees. One alphabeta dimer molecule of Hb D existed in an asymmetric unit, with a calculated value of Vm of 2.77 A(3)Da(-1). | ||
- | + | Crystallization and preliminary X-ray diffraction study of hemoglobin D from the Aldabra giant tortoise, Geochelone gigantea.,Kuwada T, Hasegawa T, Satoh I, Ishikawa K, Shishikura F Protein Pept Lett. 2003 Aug;10(4):422-5. PMID:14529497<ref>PMID:14529497</ref> | |
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- | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
- | + | </div> | |
+ | <div class="pdbe-citations 1v75" style="background-color:#fffaf0;"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Hemoglobin 3D structures|Hemoglobin 3D structures]] | |
- | [[Category: | + | == References == |
- | [[Category: | + | <references/> |
- | [[Category: Hasegawa | + | __TOC__ |
- | [[Category: Ishikawa | + | </StructureSection> |
- | [[Category: Kuwada | + | [[Category: Aldabrachelys gigantea]] |
- | [[Category: Satoh | + | [[Category: Large Structures]] |
- | [[Category: Shishikura | + | [[Category: Hasegawa T]] |
- | + | [[Category: Ishikawa K]] | |
- | + | [[Category: Kuwada T]] | |
- | + | [[Category: Satoh I]] | |
- | + | [[Category: Shishikura F]] | |
- | + |
Current revision
Crystal structure of hemoglobin D from the Aldabra giant tortoise (Geochelone gigantea) at 2.0 A resolution
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