9gd8
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==NME1 94-Diphosphoserine== | |
- | + | <StructureSection load='9gd8' size='340' side='right'caption='[[9gd8]], [[Resolution|resolution]] 3.30Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9gd8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GD8 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DISEP:2-azanyl-3-[oxidanyl(phosphonooxy)phosphoryl]oxy-propanoic+acid'>DISEP</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gd8 OCA], [https://pdbe.org/9gd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gd8 RCSB], [https://www.ebi.ac.uk/pdbsum/9gd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gd8 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/NDKA_HUMAN NDKA_HUMAN] Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.<ref>PMID:2056128</ref> <ref>PMID:8810265</ref> <ref>PMID:12628186</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Celik A]] | ||
+ | [[Category: Fiedler D]] | ||
+ | [[Category: Roderer D]] | ||
+ | [[Category: Schoepf F]] |
Current revision
NME1 94-Diphosphoserine
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