9ubi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of FERONIA kinase and Ferovicin inhibitor== | |
| - | + | <StructureSection load='9ubi' size='340' side='right'caption='[[9ubi]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ubi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UBI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OT5:1-[6-(3,5-DICHLORO-4-HYDROXYPHENYL)-4-({TRANS-4-[(DIMETHYLAMINO)METHYL]CYCLOHEXYL}AMINO)-1,5-NAPHTHYRIDIN-3-YL]ETHANONE'>OT5</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ubi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ubi OCA], [https://pdbe.org/9ubi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ubi RCSB], [https://www.ebi.ac.uk/pdbsum/9ubi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ubi ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/FERON_ARATH FERON_ARATH] Receptor-like protein kinase that mediates the female control of male gamete delivery during fertilization, including growth cessation of compatible pollen tubes ensuring a reproductive isolation barriers, by regulating MLO7 subcellular polarization upon pollen tube perception in the female gametophyte synergids. Required for cell elongation during vegetative growth, mostly in a brassinosteroids- (BR-) independent manner. Acts as an upstream regulator for the Rac/Rop-signaling pathway that controls ROS-mediated root hair development. Seems to regulate a cross-talk between brassinosteroids and ethylene signaling pathways during hypocotyl elongation. Negative regulator of brassinosteroid response in light-grown hypocotyls, but required for brassinosteroid response in etiolated seedlings. Mediates sensitivity to powdery mildew (e.g. Golovinomyces orontii). Positive regulator of auxin-promoted growth that represses the abscisic acid (ABA) signaling via the activation of ABI2 phosphatase. Required for RALF1-mediated extracellular alkalinization in a signaling pathway preventing cell expansion.<ref>PMID:17673660</ref> <ref>PMID:19383785</ref> <ref>PMID:20400488</ref> <ref>PMID:20876100</ref> <ref>PMID:21071669</ref> <ref>PMID:22908257</ref> <ref>PMID:24458638</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arabidopsis thaliana]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fan JP]] | ||
| + | [[Category: Lei XG]] | ||
| + | [[Category: Sun MZ]] | ||
Current revision
Crystal structure of FERONIA kinase and Ferovicin inhibitor
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