9nov

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'''Unreleased structure'''
 
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The entry 9nov is ON HOLD until Paper Publication
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==Human sweet taste receptor (TAS1R2 + TAS1R3) VFT domains bound to sucralose==
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<StructureSection load='9nov' size='340' side='right'caption='[[9nov]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9nov]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NOV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NOV FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PRD_900090:sucralose'>PRD_900090</scene>, <scene name='pdbligand=RRJ:4-chloro-4-deoxy-alpha-D-galactopyranose'>RRJ</scene>, <scene name='pdbligand=RRY:(2~{S},3~{S},4~{S},5~{S})-2,5-bis(chloromethyl)oxolane-2,3,4-triol'>RRY</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9nov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9nov OCA], [https://pdbe.org/9nov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9nov RCSB], [https://www.ebi.ac.uk/pdbsum/9nov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9nov ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TS1R3_HUMAN TS1R3_HUMAN] Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.<ref>PMID:11917125</ref> <ref>PMID:12892531</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chang AN]]
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[[Category: Fitzpatrick AWP]]
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[[Category: Juen Z]]
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[[Category: Lu Z]]
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[[Category: Wang B]]
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[[Category: Yu R]]
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[[Category: Zuker CS]]

Current revision

Human sweet taste receptor (TAS1R2 + TAS1R3) VFT domains bound to sucralose

PDB ID 9nov

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OCA

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