9fn6

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Current revision (06:12, 25 June 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9fn6 is ON HOLD
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==Full-length crystal structure of human Fascin 1==
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<StructureSection load='9fn6' size='340' side='right'caption='[[9fn6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Quereda-Moraleda, I., Grieco, A., Martin-Garcia, J.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9fn6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FN6 FirstGlance]. <br>
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Description: Full-length crystal structure of human Fascin 1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fn6 OCA], [https://pdbe.org/9fn6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fn6 RCSB], [https://www.ebi.ac.uk/pdbsum/9fn6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fn6 ProSAT]</span></td></tr>
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[[Category: Grieco, A]]
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</table>
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[[Category: Quereda-Moraleda, I]]
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== Function ==
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[[Category: Martin-Garcia, J.M]]
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[https://www.uniprot.org/uniprot/FSCN1_HUMAN FSCN1_HUMAN] Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.<ref>PMID:9362073</ref> <ref>PMID:9571235</ref> <ref>PMID:20137952</ref> <ref>PMID:20393565</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Grieco A]]
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[[Category: Martin-Garcia JM]]
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[[Category: Quereda-Moraleda I]]

Current revision

Full-length crystal structure of human Fascin 1

PDB ID 9fn6

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