9pgx
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of STEAP2 N-domain soaked with NADP+== | |
| - | + | <StructureSection load='9pgx' size='340' side='right'caption='[[9pgx]], [[Resolution|resolution]] 1.46Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9pgx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PGX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: Liu | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pgx OCA], [https://pdbe.org/9pgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pgx RCSB], [https://www.ebi.ac.uk/pdbsum/9pgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pgx ProSAT]</span></td></tr> |
| - | [[Category: Shin | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/STEA2_HUMAN STEA2_HUMAN] Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane (By similarity). Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity). Can also reduce Cu(2+) to Cu(1+) (By similarity).[UniProtKB:Q687X5][UniProtKB:Q8BWB6] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu A]] | ||
| + | [[Category: Shin I]] | ||
Current revision
Crystal structure of STEAP2 N-domain soaked with NADP+
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