Metabotropic glutamate receptor 3D structures
From Proteopedia
(Difference between revisions)
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**[[7dgd]] – hMGluR1 - human – Cryo EM<br /> | **[[7dgd]] – hMGluR1 - human – Cryo EM<br /> | ||
**[[7dge]] – hMGluR1 + nanobody + quisqualate – Cryo EM<br /> | **[[7dge]] – hMGluR1 + nanobody + quisqualate – Cryo EM<br /> | ||
| - | 3ks9 – hMGluR1 (mutant) + antagonist | + | **[[3ks9]] – hMGluR1 (mutant) + antagonist |
| - | [[4or2]] - hMGluR1/cytochrome b526<br /> | + | **[[4or2]] - hMGluR1/cytochrome b526<br /> |
| - | 1ewt, 1ewv - rMGluR1 LBD - rat | + | **[[1ewt]], [[1ewv]] - rMGluR1 LBD - rat |
| - | 1isr, 1ewk – rMGluR1 LBD + Glu | + | **[[1isr]], [[1ewk]] – rMGluR1 LBD + Glu |
| - | 1iss - rMGluR1 LBD + antagonist | + | **[[1iss]] - rMGluR1 LBD + antagonist |
* Metabotropic glutamate receptor 2 | * Metabotropic glutamate receptor 2 | ||
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**[[7epe]], [[7epf]] – hMGluR2 transmembrane domain + antagonist + FMN<br /> | **[[7epe]], [[7epf]] – hMGluR2 transmembrane domain + antagonist + FMN<br /> | ||
| - | + | *Metabotropic glutamate receptor 3 | |
| - | Metabotropic glutamate receptor 3 | + | |
**[[7wi6]], [[7wi8]], [[7wih]] – hMGluR3 – Cryo EM<br /> | **[[7wi6]], [[7wi8]], [[7wih]] – hMGluR3 – Cryo EM<br /> | ||
**[[5cnk]] – hMGluR3 LBD + Glu <br /> | **[[5cnk]] – hMGluR3 LBD + Glu <br /> | ||
| - | 3sm9 - hMGluR3 + antagonist | + | **[[3sm9]] - hMGluR3 + antagonist |
**[[8tqb]] – hMGluR3 + agonist – Cryo EM<br /> | **[[8tqb]] – hMGluR3 + agonist – Cryo EM<br /> | ||
**[[9ii2]], [[9ii3]] – hMGluR3 + beta-arrestin – Cryo EM<br /> | **[[9ii2]], [[9ii3]] – hMGluR3 + beta-arrestin – Cryo EM<br /> | ||
**[[4xar]], [[6b7h]] – hMGluR3 LBD + agonist<br /> | **[[4xar]], [[6b7h]] – hMGluR3 LBD + agonist<br /> | ||
**[[5cnm]] – hMGluR3 LBD + Glu analog<br /> | **[[5cnm]] – hMGluR3 LBD + Glu analog<br /> | ||
| - | 2e4u – rMGluR3 LBD (mutant) + Glu | + | **[[2e4u]] – rMGluR3 LBD (mutant) + Glu |
**[[8tr2]] – rMGluR3 + agonist – Cryo EM<br /> | **[[8tr2]] – rMGluR3 + agonist – Cryo EM<br /> | ||
**[[8tr0]], [[8trd]] – rMGluR3 + antagonist – Cryo EM<br /> | **[[8tr0]], [[8trd]] – rMGluR3 + antagonist – Cryo EM<br /> | ||
**[[8trc]] – rMGluR3 + antagonist + modulator – Cryo EM<br /> | **[[8trc]] – rMGluR3 + antagonist + modulator – Cryo EM<br /> | ||
| - | 2e4v, 2e4w, 2e4x, 2e4y, 2e4z - rMGluR3 LBD (mutant) + agonist | + | **[[2e4v]], [[2e4w]], [[2e4x]], [[2e4y]], [[2e4z]] - rMGluR3 LBD (mutant) + agonist |
*Metabotropic glutamate receptor 4 | *Metabotropic glutamate receptor 4 | ||
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**[[7e9h]] – hMGluR4 in Gi complex + antagonist + scFv – Cryo EM<br /> | **[[7e9h]] – hMGluR4 in Gi complex + antagonist + scFv – Cryo EM<br /> | ||
| - | Metabotropic glutamate receptor 5 | + | *Metabotropic glutamate receptor 5 |
**[[6n52]] – hMGluR5 – Cryo EM<br /> | **[[6n52]] – hMGluR5 – Cryo EM<br /> | ||
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**[[8t6j]] – hMGluR5 + activator – Cryo EM<br /> | **[[8t6j]] – hMGluR5 + activator – Cryo EM<br /> | ||
**[[6n4x]] – hMGluR5 LBD<br /> | **[[6n4x]] – hMGluR5 LBD<br /> | ||
| - | 3lmk – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu | + | **[[3lmk]] – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu |
**[[6ffh]], [[6ffi]] - hMGluR5 LBD (mutant) + positive allosteric modulator<br /> | **[[6ffh]], [[6ffi]] - hMGluR5 LBD (mutant) + positive allosteric modulator<br /> | ||
**[[9hc3]] - hMGluR5 transmembrane domain/endolysin<br /> | **[[9hc3]] - hMGluR5 transmembrane domain/endolysin<br /> | ||
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**[[7p2l]] - hMGluR5 transmembrane domain (mutant) + negative allosteric modulator<br /> | **[[7p2l]] - hMGluR5 transmembrane domain (mutant) + negative allosteric modulator<br /> | ||
| - | Metabotropic glutamate receptor 7 | + | *Metabotropic glutamate receptor 7 |
**[[7epc]], [[9omo]], [[9omp]] – hMGluR7 – Cryo EM<br /> | **[[7epc]], [[9omo]], [[9omp]] – hMGluR7 – Cryo EM<br /> | ||
**[[5c5c]] – hMGluR7 LBD (mutant)<br /> | **[[5c5c]] – hMGluR7 LBD (mutant)<br /> | ||
| - | 3mq4 – hMGluR7 LBD + antagonist | + | **[[3mq4]] – hMGluR7 LBD + antagonist |
*Metabotropic glutamate receptor 8 | *Metabotropic glutamate receptor 8 | ||
Current revision
3D structures of metabotropic glutamate receptor
Updated on 16-July-2025
