9s0u
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9s0u is ON HOLD Authors: Walshe, J.L., Ochmann, M., Dienemann, C., Cramer, P. Description: State 3 MAP 3 RNA Pol II activated elongation complex wi...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==State 3 MAP 3 RNA Pol II activated elongation complex with SETD2 bound to distal upstream H3== | |
| - | + | <StructureSection load='9s0u' size='340' side='right'caption='[[9s0u]], [[Resolution|resolution]] 6.72Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9s0u]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9S0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9S0U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.72Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9s0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9s0u OCA], [https://pdbe.org/9s0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9s0u RCSB], [https://www.ebi.ac.uk/pdbsum/9s0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9s0u ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Cramer | + | [https://www.uniprot.org/uniprot/A0A8D1KNW4_PIG A0A8D1KNW4_PIG] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPABC2 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds.[ARBA:ARBA00044490] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sus scrofa]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Cramer P]] | ||
| + | [[Category: Dienemann C]] | ||
| + | [[Category: Ochmann M]] | ||
| + | [[Category: Walshe JL]] | ||
Current revision
State 3 MAP 3 RNA Pol II activated elongation complex with SETD2 bound to distal upstream H3
| |||||||||||
