GTPase KRas 3D structures

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:38, 7 August 2025) (edit) (undo)
 
(One intermediate revision not shown.)
Line 4: Line 4:
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
-
*GTPase KRas binary complex with nucleotide
+
*GTPase KRas apo binary complex with nucleotide
**[[5uk9]] – hKRas + GCP + GDP – human <br />
**[[5uk9]] – hKRas + GCP + GDP – human <br />
**[[5vq2]] – hKRas + GTP <br />
**[[5vq2]] – hKRas + GTP <br />
 +
**[[6god]], [[6mbq]] – hKRas + GNP <br />
 +
**[[4lkp]], [[4obe]], [[5vq8]], [[5w22]], [[6mbt]], [[6mbu]], [[6p0z]], [[7tlk]] – hKRas + GDP <br />
 +
**[[7lgi]] – hKRas + GDP - NMR<br />
 +
**[[9o0r]], [[9o0s]] – hKRas + drug + GDP <br />
 +
**[[7mqu]] – hKRas + drug + GDP - NMR<br />
 +
 +
*GTPase KRas apo complex with inhibitor
 +
 +
**[[5kyk]] – hKRas + inhibitor <br />
 +
**[[6v5l]], [[7tle]], [[8afb]], [[8afc]], [[8afd]], [[8azr]], [[8azv]], [[8jhl]], [[8onv]], [[8s8c]], [[9bai]], [[9bak]], [[9baj]], [[9qpz]] – hKRas + GDP + inhibitor <br />
 +
 +
*GTPase KRas apo complex with protein
 +
 +
**[[6h46]] – hKRas + darpin K13 + GDP <br />
 +
**[[6h47]] – hKRas + darpin K19 <br />
 +
**[[5mlb]], [[5o2s]] – hKRas + darpin K27 + GDP <br />
 +
**[[5mla]], [[5o2t]] – hKRas + darpin 55 + GSP <br />
 +
**[[5o2s]], [[5ufe]] – hKRas + R11.1.6 + GNP <br />
 +
**[[9c15]], [[9cmv]] – hKRas + p110 alpha + GNP <br />
 +
**[[2msc]], [[2msd]] – hKRas + apolipoprotein + GDP - NMR<br />
 +
**[[2mse]] – hKRas + apolipoprotein + A-Raf + GDP - NMR<br />
 +
**[[8dgt]] – hKRas + MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM<br />
 +
**[[6pts]], [[6ptw]] – hKRas + apolipoprotein + C-Raf + GNP - NMR<br />
 +
**[[6ob2]] – hKRas + neurofibromin + GNP <br />
 +
**[[8qu8]] – hKRas + elongin B,C + pVHL + cullin-2 + Rbx1 + inhibitor + GDP – Cryo EM <br />
 +
**[[6v65]], [[6v6f]] – hKRas + neurofibromin + Hspred1 + GNP <br />
 +
**[[6yr8]], [[6yxw]], [[7ny8]] – hKRas + affirmer K6 + GDP <br />
 +
**[[8rro]] – hKRas + Tcr + HLA + microglobulin + drug + GNP <br />
 +
 +
*GTPase KRas4A apo
 +
 +
**[[8t72]] – hKRas + PNP<br />
 +
**[[8t71]] – hKRas + GDP<br />
 +
**[[8t75]] – hKRas + C-Raf + PNP<br />
 +
**[[8t74]] – hKRas + Raf1 + PNP<br />
 +
**[[7vvb]] – hKRas + SIN1 + PNP<br />
 +
**[[9g0y]], [[9g4b]], [[9ggt]], [[9ggu]], [[9ggv]], [[9ggw]], [[9ggx]], [[9ggy]], [[9ggz]], [[9gh0]], [[9gh1]], [[9gh2]] – hKRas + GDP + inhibitor<br />
 +
 +
*GTPase KRas2B apo
 +
 +
**[[7kyz]] – hKRas + GDP - NMR<br />
 +
**[[9gtk]] – hKRas + Darpin + GDP<br />
 +
 +
*GTPase KRas4B apo
 +
 +
**[[6m9w]], [[8ecr]] – hKRas + GDP<br />
 +
**[[6w4e]] – hKRas + GDP - NMR<br />
 +
**[[6vc8]] – hKRas + PNP<br />
 +
**[[8eie]] – hKRas + GNP<br />
 +
**[[5tar]], [[5tb5]], [[7q9u]] – hKRas + GMP-PDE d + farnesyl + GDP <br
 +
**[[6w4e]] – hKRas + apolipoprotein + GTP - NMR<br />
 +
**[[6w4f]] – hKRas + apolipoprotein + GDP - NMR<br />
 +
**[[6vjj]], [[6xhb]], [[6xi7]] – hKRas + Raf1/CRaf + GNP
 +
 +
*GTPase KRasX2 apo
 +
 +
**[[8dgs]], [[8dgt]] – hKRas + MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM<br />
 +
 +
*GTPase KRas with oncogenic mutated 12G binary complex with nucleotide
 +
**[[5vpi]], [[5vpz]], [[5vq6]], [[6mnx]] – hKRas (mutant) + GTP <br />
**[[5vpi]], [[5vpz]], [[5vq6]], [[6mnx]] – hKRas (mutant) + GTP <br />
**[[3gft]], [[6mta]] – hKRas (mutant) + GTP analog <br />
**[[3gft]], [[6mta]] – hKRas (mutant) + GTP analog <br />
-
**[[6god]], [[6mbq]] – hKRas + GNP <br />
 
**[[5usj]], [[5vpy]], [[6e6f]], [[6goe]], [[6gof]], [[6gog]], [[6gom]], [[6o36]], [[6o46]], [[8ebz]] – hKRas (mutant) + GNP <br />
**[[5usj]], [[5vpy]], [[6e6f]], [[6goe]], [[6gof]], [[6gog]], [[6gom]], [[6o36]], [[6o46]], [[8ebz]] – hKRas (mutant) + GNP <br />
-
**[[4lkp]], [[4obe]], [[5vq8]], [[5w22]], [[6mbt]], [[6mbu]], [[6p0z]], [[7tlk]] – hKRas + GDP <br />
 
**[[4l8g]], [[4ldj]], [[4lrw]], [[4ql3]], [[4tq9]], [[4wa7]], [[5uqw]], [[5us4]], [[5vp7]], [[5vq0]], [[5vq1]], [[5whd]], [[6asa]], [[6ase]], [[6bof]], [[6e6g]], [[6mqg]], [[6mqn]], [[6ms9]], [[6pq3]], [[6ws2]], [[6ws4]], [[7c40]], [[7eyx]], [[7f0w]], [[7kmr]], [[8fmi]], [[8fmj]], [[8fmk]], [[8g4f]], [[8stm]], [[8stn]], [[8tvk]], [[8txj]], [[8ty2]], [[8ty8]], [[8ty9]] – hKRas (mutant) + GDP <br />
**[[4l8g]], [[4ldj]], [[4lrw]], [[4ql3]], [[4tq9]], [[4wa7]], [[5uqw]], [[5us4]], [[5vp7]], [[5vq0]], [[5vq1]], [[5whd]], [[6asa]], [[6ase]], [[6bof]], [[6e6g]], [[6mqg]], [[6mqn]], [[6ms9]], [[6pq3]], [[6ws2]], [[6ws4]], [[7c40]], [[7eyx]], [[7f0w]], [[7kmr]], [[8fmi]], [[8fmj]], [[8fmk]], [[8g4f]], [[8stm]], [[8stn]], [[8tvk]], [[8txj]], [[8ty2]], [[8ty8]], [[8ty9]] – hKRas (mutant) + GDP <br />
**[[7g42]], [[8g47]], [[8g4h]] – hKRas (mutant) + GDP – Cryo EM<br />
**[[7g42]], [[8g47]], [[8g4h]] – hKRas (mutant) + GDP – Cryo EM<br />
-
**[[7lgi]] – hKRas + GDP - NMR<br />
 
-
**[[9o0r]], [[9o0s]] – hKRas + drug + GDP <br />
 
**[[9dmm]] – hKRas (mutant) + drug + GDP <br />
**[[9dmm]] – hKRas (mutant) + drug + GDP <br />
-
**[[7mqu]] – hKRas + drug + GDP - NMR<br />
 
**[[4dsn]], [[6bp1]], [[6quu]] – hKRas (mutant) + GCP <br />
**[[4dsn]], [[6bp1]], [[6quu]] – hKRas (mutant) + GCP <br />
**[[7lz5]] – hKRas (mutant) + GMPPCP <br />
**[[7lz5]] – hKRas (mutant) + GMPPCP <br />
-
*GTPase KRas complex with inhibitor
+
*GTPase KRas with oncogenic mutated 12G complex with inhibitor
**[[4dso]] – hKRas (mutant) + inhibitor + GSP <br />
**[[4dso]] – hKRas (mutant) + inhibitor + GSP <br />
**[[4dst]], [[6gj5]], [[6gj6]], [[6gj7]], [[6gj8]], [[6quv]], [[6quw]], [[6qux]] – hKRas (mutant) + inhibitor + GCP <br />
**[[4dst]], [[6gj5]], [[6gj6]], [[6gj7]], [[6gj8]], [[6quv]], [[6quw]], [[6qux]] – hKRas (mutant) + inhibitor + GCP <br />
-
**[[5kyk]] – hKRas + inhibitor <br />
 
**[[4nmm]], [[7ok3]], [[7ok4]] – hKRas (mutant) + inhibitor <br />
**[[4nmm]], [[7ok3]], [[7ok4]] – hKRas (mutant) + inhibitor <br />
-
**[[6v5l]], [[7tle]], [[8afb]], [[8afc]], [[8afd]], [[8azr]], [[8azv]], [[8jhl]], [[8onv]], [[8s8c]], [[9bai]], [[9bak]], [[9baj]], [[9qpz]] – hKRas + GDP + inhibitor <br />
 
**[[4dsu]], [[4luc]], [[4lv6]], [[4lyf]], [[4lyh]], [[4lyj]], [[4m1o]], [[4m1s]], [[4m1t]], [[4m1w]], [[4m1y]], [[4m21]], [[4m22]], [[4epr]], [[4ept]], [[4epv]], [[4epw]], [[4epx]], [[4epy]], [[4q01]], [[4q02]], [[4q03]], [[4pzy]], [[4pzz]], [[5f2e]], [[5vbm]], [[5v6s]], [[5v6v]], [[5v9o]], [[5v9u]], [[5xco]], [[5yxz]], [[5yy1]], [[6ark]], [[6b0v]], [[6b0y]], [[6n2j]], [[6n2k]], [[6oim]], [[6p8w]], [[6p8x]], [[6p8y]], [[6p8z]], [[6pgo]], [[6pgp]], [[6t5b]], [[6tam]], [[6tan]], [[6usx]], [[6usz]], [[6ut0]], [[6zl5]], [[7a1w]], [[7a1x]], [[7a1y]], [[7a47]], [[7acq]], [[7ew9]], [[7ewa]], [[7ewb]], [[7o70]], [[7oo7]], [[7r0m]], [[7r0n]], [[7r0q]], [[7rp4]], [[7tlg]], [[7u8h]], [[7ycc]], [[7yce]], [[8aq5]], [[8aq7]], [[8azx]], [[8azy]], [[8azz]], [[8b00]], [[8b6i]], [[8b78]], [[8cx5]], [[8dni]], [[8dnj]], [[8dnk]], [[8qug]], [[8r7w]], [[8r7x]], [[8t4v]], [[8txe]], [[8txg]], [[8txh]], [[8txk]], [[8un3]], [[8un4]], [[8un5]], [[8v3a]], [[8wb1]], [[8x6r]], [[9bl0]], [[9e5d]], [[9e5f]], [[9e9h]], [[9e9i]], [[9gbj]], [[9kpn]], [[9u50]], [[9u5t]] – hKRas (mutant) + GDP + inhibitor <br />
**[[4dsu]], [[4luc]], [[4lv6]], [[4lyf]], [[4lyh]], [[4lyj]], [[4m1o]], [[4m1s]], [[4m1t]], [[4m1w]], [[4m1y]], [[4m21]], [[4m22]], [[4epr]], [[4ept]], [[4epv]], [[4epw]], [[4epx]], [[4epy]], [[4q01]], [[4q02]], [[4q03]], [[4pzy]], [[4pzz]], [[5f2e]], [[5vbm]], [[5v6s]], [[5v6v]], [[5v9o]], [[5v9u]], [[5xco]], [[5yxz]], [[5yy1]], [[6ark]], [[6b0v]], [[6b0y]], [[6n2j]], [[6n2k]], [[6oim]], [[6p8w]], [[6p8x]], [[6p8y]], [[6p8z]], [[6pgo]], [[6pgp]], [[6t5b]], [[6tam]], [[6tan]], [[6usx]], [[6usz]], [[6ut0]], [[6zl5]], [[7a1w]], [[7a1x]], [[7a1y]], [[7a47]], [[7acq]], [[7ew9]], [[7ewa]], [[7ewb]], [[7o70]], [[7oo7]], [[7r0m]], [[7r0n]], [[7r0q]], [[7rp4]], [[7tlg]], [[7u8h]], [[7ycc]], [[7yce]], [[8aq5]], [[8aq7]], [[8azx]], [[8azy]], [[8azz]], [[8b00]], [[8b6i]], [[8b78]], [[8cx5]], [[8dni]], [[8dnj]], [[8dnk]], [[8qug]], [[8r7w]], [[8r7x]], [[8t4v]], [[8txe]], [[8txg]], [[8txh]], [[8txk]], [[8un3]], [[8un4]], [[8un5]], [[8v3a]], [[8wb1]], [[8x6r]], [[9bl0]], [[9e5d]], [[9e5f]], [[9e9h]], [[9e9i]], [[9gbj]], [[9kpn]], [[9u50]], [[9u5t]] – hKRas (mutant) + GDP + inhibitor <br />
**[[5ocg]], [[5oco]], [[5oct]], [[5vbz]], [[6f76]], [[6fa1]], [[6fa2]], [[6fa3]], [[6fa4]], [[6gqt]], [[6gqx]], [[6gqw]], [[6gqy]], [[8jgd]], [[8v39]] – hKRas (mutant) + GNP + inhibitor <br />
**[[5ocg]], [[5oco]], [[5oct]], [[5vbz]], [[6f76]], [[6fa1]], [[6fa2]], [[6fa3]], [[6fa4]], [[6gqt]], [[6gqx]], [[6gqw]], [[6gqy]], [[8jgd]], [[8v39]] – hKRas (mutant) + GNP + inhibitor <br />
Line 36: Line 89:
**[[5v71]], [[5v9l]], [[6t5v]] – hKRas (mutant) + GDP + quinazoline inhibitor <br />
**[[5v71]], [[5v9l]], [[6t5v]] – hKRas (mutant) + GDP + quinazoline inhibitor <br />
-
*GTPase KRas complex with protein
+
*GTPase KRas with oncogenic mutated 12G complex with protein
**[[5wha]], [[5whb]] – hKRas (mutant) + miniprotein + GDP <br />
**[[5wha]], [[5whb]] – hKRas (mutant) + miniprotein + GDP <br />
**[[5whe]], [[5wlb]], [[5wpl]], [[5wpm]] – hKRas (mutant) + miniprotein + GNP <br />
**[[5whe]], [[5wlb]], [[5wpl]], [[5wpm]] – hKRas (mutant) + miniprotein + GNP <br />
-
**[[6h46]] – hKRas + darpin K13 + GDP <br />
 
-
**[[6h47]] – hKRas + darpin K19 <br />
 
-
**[[5mlb]], [[5o2s]] – hKRas + darpin K27 + GDP <br />
 
-
**[[5mla]], [[5o2t]] – hKRas + darpin 55 + GSP <br />
 
**[[7scw]], [[7scx]] – hKRas (mutant) + RALGDS-like + GSP <br />
**[[7scw]], [[7scx]] – hKRas (mutant) + RALGDS-like + GSP <br />
-
**[[5o2s]], [[5ufe]] – hKRas + R11.1.6 + GNP <br />
 
**[[5ufq]] – hKRas (mutant) + R11.1.6 + GNP <br />
**[[5ufq]] – hKRas (mutant) + R11.1.6 + GNP <br />
**[[6wgn]] – hKRas (mutant) + peptide inhibitor + GNP <br />
**[[6wgn]] – hKRas (mutant) + peptide inhibitor + GNP <br />
-
**[[9c15]], [[9cmv]] – hKRas + p110 alpha + GNP <br />
 
**[[7c41]], [[7w5r]], [[7yuz]] – hKRas (mutant) + peptide inhibitor + GDP <br />
**[[7c41]], [[7w5r]], [[7yuz]] – hKRas (mutant) + peptide inhibitor + GDP <br />
**[[7mdp]], [[7rp2]], [[7rp3]] – hKRas (mutant) + antibody + GDP <br />
**[[7mdp]], [[7rp2]], [[7rp3]] – hKRas (mutant) + antibody + GDP <br />
Line 55: Line 102:
**[[8f0m]] – hKRas (mutant) + monobody + GDP <br />
**[[8f0m]] – hKRas (mutant) + monobody + GDP <br />
**[[8be4]], [[8be5]] – hKRas (mutant) + nanobody + son of sevenless + GDP <br />
**[[8be4]], [[8be5]] – hKRas (mutant) + nanobody + son of sevenless + GDP <br />
- 
**[[7rov]] – hKRas (mutant) + peptide inhibitor + GMPPCP <br />
**[[7rov]] – hKRas (mutant) + peptide inhibitor + GMPPCP <br />
**[[8jjs]] – hKRas (mutant) + peptide inhibitor + GDP <br />
**[[8jjs]] – hKRas (mutant) + peptide inhibitor + GDP <br />
-
 
+
+ MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM<br />
-
**[[2msc]], [[2msd]] – hKRas + apolipoprotein + GDP - NMR<br />
+
-
**[[2mse]] – hKRas + apolipoprotein + A-Raf + GDP - NMR<br />
+
-
**[[8dgt]] – hKRas + MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM<br />
+
**[[6xgu]], [[6xgv]] – hKRas (mutant) + C-Raf + GNP<br />
**[[6xgu]], [[6xgv]] – hKRas (mutant) + C-Raf + GNP<br />
-
**[[6pts]], [[6ptw]] – hKRas + apolipoprotein + C-Raf + GNP - NMR<br />
 
**[[6cc9]], [[6cch]], [[6ccx]] – hKRas (mutant) + apolipoprotein + inhibitor + GNP - NMR<br />
**[[6cc9]], [[6cch]], [[6ccx]] – hKRas (mutant) + apolipoprotein + inhibitor + GNP - NMR<br />
**[[6epl]] – hKRas (mutant) + son of sevenless homolog 1<br />
**[[6epl]] – hKRas (mutant) + son of sevenless homolog 1<br />
**[[7kfz]] – hKRas (mutant) + son of sevenless homolog 1 + GNP<br />
**[[7kfz]] – hKRas (mutant) + son of sevenless homolog 1 + GNP<br />
**[[6epm]], [[6epn]], [[6epo]], [[6epp]] – hKRas (mutant) + son of sevenless homolog 1 + inhibitor<br />
**[[6epm]], [[6epn]], [[6epo]], [[6epp]] – hKRas (mutant) + son of sevenless homolog 1 + inhibitor<br />
-
**[[6ob2]] – hKRas + neurofibromin + GNP <br />
 
**[[6ob3]] – hKRas (mutant) + neurofibromin + GNP <br />
**[[6ob3]] – hKRas (mutant) + neurofibromin + GNP <br />
**[[8qvu]], [[8qw6]], [[8qw7]] – hKRas (mutant) + elongin B,C + pVHL + GDP <br />
**[[8qvu]], [[8qw6]], [[8qw7]] – hKRas (mutant) + elongin B,C + pVHL + GDP <br />
-
**[[8qu8]] – hKRas + elongin B,C + pVHL + cullin-2 + Rbx1 + inhibitor + GDP – Cryo EM <br />
 
-
**[[6v65]], [[6v6f]] – hKRas + neurofibromin + Hspred1 + GNP <br />
 
-
**[[6yr8]], [[6yxw]], [[7ny8]] – hKRas + affirmer K6 + GDP <br />
 
**[[9bgh]], [[9bho]], [[9bhp]], [[9bhq]] – hKRas (mutant) + PPIASE + inhibitor + GDP <br />
**[[9bgh]], [[9bho]], [[9bhp]], [[9bhq]] – hKRas (mutant) + PPIASE + inhibitor + GDP <br />
**[[8g9p]], [[8g9q]], [[8tbf]], [[8tbh]], [[8tbj]], [[8tbk]], [[8tbl]], [[8tbm]], [[8tbn]], [[9ax6]], [[9bfv]], [[9bfw]], [[9bfx]], [[9bfy]], [[9bfz]], [[9bg1]], [[9bg2]], [[9bg4]], [[9bg7]], [[9bi1]], [[9bi2]], [[9ct7]], [[9e3s]] – hKRas (mutant) + PPIASE + inhibitor + GNP <br />
**[[8g9p]], [[8g9q]], [[8tbf]], [[8tbh]], [[8tbj]], [[8tbk]], [[8tbl]], [[8tbm]], [[8tbn]], [[9ax6]], [[9bfv]], [[9bfw]], [[9bfx]], [[9bfy]], [[9bfz]], [[9bg1]], [[9bg2]], [[9bg4]], [[9bg7]], [[9bi1]], [[9bi2]], [[9ct7]], [[9e3s]] – hKRas (mutant) + PPIASE + inhibitor + GNP <br />
**[[9bg5]], [[9bg6]], [[9bga]], [[9bgb]], [[9bgc]], [[9ct8]], [[9ct9]], [[9cta]], [[9ctb]] – hKRas (mutant) + PPIASE + drug + GNP <br />
**[[9bg5]], [[9bg6]], [[9bga]], [[9bgb]], [[9bgc]], [[9ct8]], [[9ct9]], [[9cta]], [[9ctb]] – hKRas (mutant) + PPIASE + drug + GNP <br />
-
**[[8rro]] – hKRas + Tcr + HLA + microglobulin + drug + GNP <br />
 
**[[6t5u]] – KRas (mutant) + V-ki-ras2 + inhibitor + GDP -hedgehog <br />
**[[6t5u]] – KRas (mutant) + V-ki-ras2 + inhibitor + GDP -hedgehog <br />
-
*GTPase KRas4A
+
*GTPase KRas4A with oncogenic mutated 12G
-
**[[8t72]] – hKRas + PNP<br />
 
-
**[[8t71]] – hKRas + GDP<br />
 
**[[8t73]] – hKRas (mutant) + GDP<br />
**[[8t73]] – hKRas (mutant) + GDP<br />
-
**[[8t75]] – hKRas + C-Raf + PNP<br />
 
-
**[[8t74]] – hKRas + Raf1 + PNP<br />
 
-
**[[7vvb]] – hKRas + SIN1 + PNP<br />
 
-
**[[9g0y, [[9g4b]], [[9ggt]], [[9ggu]], [[9ggv]], [[9ggw]], [[9ggx]], [[9ggy]], [[9ggz]], [[9gh0]], [[9gh1]], [[9gh2]] – hKRas + GDP + inhibitor<br />
 
-
*GTPase KRas2B
+
*GTPase KRas4B with oncogenic mutated 12G
-
**[[7kyz]] – hKRas + GDP - NMR<br />
 
-
**[[9gtk]] – hKRas + Darpin + GDP<br />
 
- 
-
*GTPase KRas4B
 
- 
-
**[[6m9w]], [[8ecr]] – hKRas + GDP<br />
 
-
**[[6w4e]] – hKRas + GDP - NMR<br />
 
**[[7t1f]], [[8blr]], [[8cpr]], [[8edy]], [[8eer]] – hKRas (mutant) + GDP<br />
**[[7t1f]], [[8blr]], [[8cpr]], [[8edy]], [[8eer]] – hKRas (mutant) + GDP<br />
-
**[[6vc8]] – hKRas + PNP<br />
 
**[[6cu6]] – hKRas (mutant) + PNP<br />
**[[6cu6]] – hKRas (mutant) + PNP<br />
-
**[[8eie]] – hKRas + GNP<br />
 
-
**[[5tar]], [[5tb5]], [[7q9u]] – hKRas + GMP-PDE d + farnesyl + GDP <br
 
**[[8b69]] – hKRas (mutant) + Rgl2 + GNP <br />
**[[8b69]] – hKRas (mutant) + Rgl2 + GNP <br />
-
**[[6w4e]] – hKRas + apolipoprotein + GTP - NMR<br />
 
-
**[[6w4f]] – hKRas + apolipoprotein + GDP - NMR<br />
 
**[[7rsc]], [[7rse]] – hKRas (mutant) + apolipoprotein + GSP - NMR<br />
**[[7rsc]], [[7rse]] – hKRas (mutant) + apolipoprotein + GSP - NMR<br />
-
**[[6vjj]], [[6xhb]], [[6xi7]] – hKRas + Raf1/CRaf + GNP
 
**[[6xha]], [[8epw]] – hKRas (mutant) + Raf1/CRaf + PNP
**[[6xha]], [[8epw]] – hKRas (mutant) + Raf1/CRaf + PNP
**[[7lc1]], [[7lc2]] – hKRas (mutant) + SIN1+ GNP <br />
**[[7lc1]], [[7lc2]] – hKRas (mutant) + SIN1+ GNP <br />
**[[7rpz]], [[7rt1]], [[7rt2]], [[7rt3]], [[7rt4]], [[7rt5]], [[9kpm]], [[9kpn]] – hKRas (mutant) + GDP + inhibitor<br />
**[[7rpz]], [[7rt1]], [[7rt2]], [[7rt3]], [[7rt4]], [[7rt5]], [[9kpm]], [[9kpn]] – hKRas (mutant) + GDP + inhibitor<br />
- 
-
*GTPase KRasX2
 
- 
-
**[[8dgs]], [[8dgt]] – hKRas + MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM<br />
 
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of GTPase KRas

Updated on 07-August-2025

+ MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Personal tools