9q35

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m (Protected "9q35" [edit=sysop:move=sysop])
Current revision (05:47, 24 September 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9q35 is ON HOLD
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==Fibrinogen domain dimer from human Fibrinogen-like protein 1 (FGL-1)==
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<StructureSection load='9q35' size='340' side='right'caption='[[9q35]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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Authors: Nyovanie, S., Patskovsky, Y., Krogsgaard, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9q35]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Q35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Q35 FirstGlance]. <br>
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Description: Fibrinogen domain dimer from human Fibrinogen-like protein 1 (FGL-1)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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[[Category: Nyovanie, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9q35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9q35 OCA], [https://pdbe.org/9q35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9q35 RCSB], [https://www.ebi.ac.uk/pdbsum/9q35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9q35 ProSAT]</span></td></tr>
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[[Category: Krogsgaard, M]]
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</table>
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[[Category: Patskovsky, Y]]
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== Function ==
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[https://www.uniprot.org/uniprot/FGL1_HUMAN FGL1_HUMAN] Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). Secreted by, and promotes growth of, hepatocytes (PubMed:11470158, PubMed:19880967).<ref>PMID:11470158</ref> <ref>PMID:19880967</ref> <ref>PMID:30580966</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Krogsgaard M]]
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[[Category: Nyovanie S]]
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[[Category: Patskovsky Y]]

Current revision

Fibrinogen domain dimer from human Fibrinogen-like protein 1 (FGL-1)

PDB ID 9q35

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OCA

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