1xxq

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[[Image:1xxq.gif|left|200px]]
 
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==Structure of a mannose-specific jacalin-related lectin from Morus nigra==
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The line below this paragraph, containing "STRUCTURE_1xxq", creates the "Structure Box" on the page.
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<StructureSection load='1xxq' size='340' side='right'caption='[[1xxq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xxq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Morus_nigra Morus nigra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XXQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1xxq| PDB=1xxq | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xxq OCA], [https://pdbe.org/1xxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xxq RCSB], [https://www.ebi.ac.uk/pdbsum/1xxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xxq ProSAT]</span></td></tr>
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</table>
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'''Structure of a mannose-specific jacalin-related lectin from Morus nigra'''
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== Function ==
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[https://www.uniprot.org/uniprot/Q8LGR3_MORNI Q8LGR3_MORNI]
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== Evolutionary Conservation ==
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==Overview==
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[[Image:Consurf_key_small.gif|200px|right]]
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The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins.
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xx/1xxq_consurf.spt"</scriptWhenChecked>
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1XXQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Morus_nigra Morus nigra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXQ OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose., Rabijns A, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Rouge P, FEBS J. 2005 Jul;272(14):3725-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16008570 16008570]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xxq ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Morus nigra]]
[[Category: Morus nigra]]
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[[Category: Single protein]]
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[[Category: Barre A]]
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[[Category: Barre, A.]]
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[[Category: De Ranter CJ]]
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[[Category: Damme, E J.M Van.]]
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[[Category: Peumans WJ]]
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[[Category: Peumans, W J.]]
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[[Category: Rabijns A]]
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[[Category: Rabijns, A.]]
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[[Category: Rouge P]]
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[[Category: Ranter, C J.De.]]
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[[Category: Van Damme EJM]]
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[[Category: Rouge, P.]]
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[[Category: Jacalin-fold]]
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[[Category: Tetrameric b-prism fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:38:27 2008''
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Current revision

Structure of a mannose-specific jacalin-related lectin from Morus nigra

PDB ID 1xxq

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