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2bbw
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2bbw" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bbw, resolution 2.05Å" /> '''Crystal structure o...) |
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| - | [[Image:2bbw.gif|left|200px]]<br /> | ||
| - | <applet load="2bbw" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2bbw, resolution 2.05Å" /> | ||
| - | '''Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate'''<br /> | ||
| - | == | + | ==Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate== |
| - | + | <StructureSection load='2bbw' size='340' side='right'caption='[[2bbw]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[ | + | <table><tr><td colspan='2'>[[2bbw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBW FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GP5:DIGUANOSINE-PENTAPHOSPHATE'>GP5</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbw OCA], [https://pdbe.org/2bbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbw RCSB], [https://www.ebi.ac.uk/pdbsum/2bbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbw ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/KAD4_HUMAN KAD4_HUMAN] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP (By similarity). | |
| - | [ | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/2bbw_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[ | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bbw ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | + | ||
| - | + | ||
| - | [ | + | |
| - | [[ | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith C]] | ||
| + | [[Category: Bunkoczi G]] | ||
| + | [[Category: Debreczeni J]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Fedorov O]] | ||
| + | [[Category: Filippakopoulos P]] | ||
| + | [[Category: Knapp S]] | ||
| + | [[Category: Niesen F]] | ||
| + | [[Category: Sundstrom M]] | ||
| + | [[Category: Turnbull AP]] | ||
| + | [[Category: Ugochukwu E]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Bunkoczi G | Debreczeni J | Edwards A | Fedorov O | Filippakopoulos P | Knapp S | Niesen F | Sundstrom M | Turnbull AP | Ugochukwu E | Weigelt J | Von Delft F
