1yq8

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[[Image:1yq8.gif|left|200px]]
 
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==PRD1 vertex protein P5==
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The line below this paragraph, containing "STRUCTURE_1yq8", creates the "Structure Box" on the page.
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<StructureSection load='1yq8' size='340' side='right'caption='[[1yq8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yq8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_PRD1 Enterobacteria phage PRD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YQ8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yq8 OCA], [https://pdbe.org/1yq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yq8 RCSB], [https://www.ebi.ac.uk/pdbsum/1yq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yq8 ProSAT]</span></td></tr>
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{{STRUCTURE_1yq8| PDB=1yq8 | SCENE= }}
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</table>
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== Function ==
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'''PRD1 vertex protein P5'''
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[https://www.uniprot.org/uniprot/P5_BPPRD P5_BPPRD] In association with P31 and P2, forms the spike complexes located at the 5-fold vertices of the capsid. Essential for viral infectivity.<ref>PMID:10956048</ref>
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== References ==
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<references/>
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==Overview==
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__TOC__
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Comparisons of bacteriophage PRD1 and adenovirus protein structures and virion architectures have been instrumental in unraveling an evolutionary relationship and have led to a proposal of a phylogeny-based virus classification. The structure of the PRD1 spike protein P5 provides further insight into the evolution of viral proteins. The crystallized P5 fragment comprises two structural domains: a globular knob and a fibrous shaft. The head folds into a ten-stranded jelly roll beta barrel, which is structurally related to the tumor necrosis factor (TNF) and the PRD1 coat protein domains. The shaft domain is a structural counterpart to the adenovirus spike shaft. The structural relationships between PRD1, TNF, and adenovirus proteins suggest that the vertex proteins may have originated from an ancestral TNF-like jelly roll coat protein via a combination of gene duplication and deletion.
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</StructureSection>
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[[Category: Enterobacteria phage PRD1]]
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==About this Structure==
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[[Category: Large Structures]]
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1YQ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_prd1 Enterobacteria phage prd1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQ8 OCA].
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[[Category: Bamford DH]]
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[[Category: Goldman A]]
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==Reference==
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[[Category: Huiskonen JT]]
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The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture., Merckel MC, Huiskonen JT, Bamford DH, Goldman A, Tuma R, Mol Cell. 2005 Apr 15;18(2):161-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15837420 15837420]
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[[Category: Merckel MC]]
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[[Category: Enterobacteria phage prd1]]
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[[Category: Tuma R]]
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[[Category: Single protein]]
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[[Category: Bamford, D H.]]
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[[Category: Goldman, A.]]
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[[Category: Huiskonen, J T.]]
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[[Category: Merckel, M C.]]
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[[Category: Tuma, R.]]
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[[Category: Beta-spiral beta-jelly-roll]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 16:38:32 2008''
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Current revision

PRD1 vertex protein P5

PDB ID 1yq8

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