2cqb
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2cqb" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cqb" /> '''Solution Structure of the RNA recognition m...) |
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- | [[Image:2cqb.gif|left|200px]]<br /> | ||
- | <applet load="2cqb" size="450" color="white" frame="true" align="right" spinBox="true" | ||
- | caption="2cqb" /> | ||
- | '''Solution Structure of the RNA recognition motif in Peptidyl-prolyl cis-trans isomerase E'''<br /> | ||
- | == | + | ==Solution Structure of the RNA recognition motif in Peptidyl-prolyl cis-trans isomerase E== |
- | + | <StructureSection load='2cqb' size='340' side='right'caption='[[2cqb]]' scene=''> | |
- | + | == Structural highlights == | |
- | [ | + | <table><tr><td colspan='2'>[[2cqb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CQB FirstGlance]. <br> |
- | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cqb OCA], [https://pdbe.org/2cqb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cqb RCSB], [https://www.ebi.ac.uk/pdbsum/2cqb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cqb ProSAT], [https://www.topsan.org/Proteins/RSGI/2cqb TOPSAN]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | [ | + | [https://www.uniprot.org/uniprot/PPIE_HUMAN PPIE_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Combines RNA-binding and PPIase activities. May be involved in muscle- and brain-specific processes. May be involved in pre-mRNA splicing. |
- | + | == Evolutionary Conservation == | |
- | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/2cqb_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
- | [[ | + | </jmolCheckbox> |
- | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cqb ConSurf]. |
- | + | <div style="clear:both"></div> | |
- | + | ==See Also== | |
+ | *[[Cyclophilin 3D structures|Cyclophilin 3D structures]] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Inoue M]] | ||
+ | [[Category: Kigawa T]] | ||
+ | [[Category: Muto Y]] | ||
+ | [[Category: Shirouzu M]] | ||
+ | [[Category: Someya T]] | ||
+ | [[Category: Terada T]] | ||
+ | [[Category: Yokoyama S]] |
Current revision
Solution Structure of the RNA recognition motif in Peptidyl-prolyl cis-trans isomerase E
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Categories: Homo sapiens | Large Structures | Inoue M | Kigawa T | Muto Y | Shirouzu M | Someya T | Terada T | Yokoyama S