Template:STRUCTURE 1zpd

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1zpd, resolution 1.86Å ()

Ligands:

, ,

Activity:

Pyruvate decarboxylase, with EC number 4.1.1.1

Structural annotation:
Resources:	CATH : 1Zpda01, 1Zpda03, 1Zpda02, 1Zpdb01, 1Zpdb02, 1Zpdb03, 1Zpde02, 1Zpde03, 1Zpde01, 1Zpdf03, 1Zpdf01, 1Zpdf02 InterPro : Ipr012000, Ipr000399, Ipr012001, Ipr011766, Ipr012110 Pfam : PF02775, PF02776, PF00205 SCOP : d1zpda1, d1zpda3, d1zpda2, d1zpdb1, d1zpdb3, d1zpdb2, d1zpde3, d1zpde2, d1zpde1, d1zpdf1, d1zpdf2, d1zpdf3 UniProt : P06672

Functional annotation:
Molecular function:	magnesium ion binding carboxy-lyase activity thiamin pyrophosphate binding lyase activity pyruvate decarboxylase activity metal ion binding transferase activity catalytic activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

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OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1zpd"

@@ Line 1: / Line 1: @@
 {{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1zpd, resolution 1.86&Aring; (<scene name='initialview01'>initial scene</scene>)
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1zpd]], [[Resolution|resolution]] 1.86&Aring; (<scene name='initialview01'>default scene</scene>)}}}
-|SITE=
 |LIGAND= <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=DPX:MONO-{4-[(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-AMINO]-2-HYDROXY-3-MERCAPTO-PENT-3-ENYL-PHOSPHONO}+ESTER'>DPX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span>
-|GENE=
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02776 TPP_enzyme_N], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02005 TPP_PDC_IPDC], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00205 TPP_enzyme_M], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3961 COG3961]</span>
-|RELATEDENTRY=
 |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpd OCA], [http://www.ebi.ac.uk/pdbsum/1zpd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zpd RCSB]</span>
+|FUNCTION={{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0016831 | text = carboxy-lyase activity}}{{GO|id=GO:0030976 | text = thiamin pyrophosphate binding}}{{GO|id=GO:0016829 | text = lyase activity}}{{GO|id=GO:0004737 | text = pyruvate decarboxylase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0003824 | text = catalytic activity}}
+|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdA01 1Zpda01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdA03 1Zpda03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdA02 1Zpda02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdB01 1Zpdb01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdB02 1Zpdb02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdB03 1Zpdb03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdE02 1Zpde02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdE03 1Zpde03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdE01 1Zpde01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdF03 1Zpdf03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdF01 1Zpdf01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1zpdF02 1Zpdf02]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012000 Ipr012000], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000399 Ipr000399], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012001 Ipr012001], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011766 Ipr011766], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012110 Ipr012110]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF02775 PF02775], [http://pfam.sanger.ac.uk/family?acc=PF02776 PF02776], [http://pfam.sanger.ac.uk/family?acc=PF00205 PF00205]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31741 d1zpda1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31786 d1zpda3], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31785 d1zpda2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31742 d1zpdb1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31788 d1zpdb3], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31787 d1zpdb2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31790 d1zpde3], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31789 d1zpde2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31743 d1zpde1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31744 d1zpdf1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31791 d1zpdf2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=31792 d1zpdf3]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P06672 P06672]</span>
+|uPDB=1ZPD|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1zpd_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_1zpd_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>C [x]</text>
+<name>jmb_1zpd_C</name>
+<title>toggle chain C</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>D [x]</text>
+<name>jmb_1zpd_D</name>
+<title>toggle chain D</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1zpd

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