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2d8n
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2d8n" size="450" color="white" frame="true" align="right" spinBox="true" caption="2d8n, resolution 2.20Å" /> '''Crystal structure o...) |
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| - | [[Image:2d8n.gif|left|200px]]<br /> | ||
| - | <applet load="2d8n" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2d8n, resolution 2.20Å" /> | ||
| - | '''Crystal structure of human recoverin at 2.2 A resolution'''<br /> | ||
| - | == | + | ==Crystal structure of human recoverin at 2.2 A resolution== |
| - | + | <StructureSection load='2d8n' size='340' side='right'caption='[[2d8n]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2d8n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D8N FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d8n OCA], [https://pdbe.org/2d8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d8n RCSB], [https://www.ebi.ac.uk/pdbsum/2d8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d8n ProSAT], [https://www.topsan.org/Proteins/RSGI/2d8n TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/RECO_HUMAN RECO_HUMAN] Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse. | |
| - | [ | + | == Evolutionary Conservation == |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/2d8n_consurf.spt"</scriptWhenChecked> |
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d8n ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Recoverin%2C a calcium-activated myristoyl switch|Recoverin%2C a calcium-activated myristoyl switch]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kamo S]] | ||
| + | [[Category: Kishishita S]] | ||
| + | [[Category: Murayama K]] | ||
| + | [[Category: Shirouzu M]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Crystal structure of human recoverin at 2.2 A resolution
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