238d

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[[Image:238d.jpg|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA==
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The line below this paragraph, containing "STRUCTURE_238d", creates the "Structure Box" on the page.
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<StructureSection load='238d' size='340' side='right'caption='[[238d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[238d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=238D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=238D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr>
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{{STRUCTURE_238d| PDB=238d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=238d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=238d OCA], [https://pdbe.org/238d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=238d RCSB], [https://www.ebi.ac.uk/pdbsum/238d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=238d ProSAT]</span></td></tr>
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</table>
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'''CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA'''
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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==Overview==
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[[Category: Nunn CM]]
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The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no cobalt hexammine ions are bound to the DNA structure. This contrasts with the recently determined crystal structure of d(AGGCATGCCT) which has a similar DNA conformation and cobalt hexammine ions bound directly to the DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of the crystal packing of this sequence leads to an understanding of how cobalt hexammine binding to DNA occurs and its role in determining DNA conformation.
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==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=238D OCA].
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==Reference==
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Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA., Nunn CM, J Biomol Struct Dyn. 1996 Aug;14(1):49-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8877561 8877561]
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[[Category: Nunn, C M.]]
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[[Category: A-dna]]
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[[Category: Base triplet]]
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[[Category: Double helix]]
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[[Category: Flipped-out base]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:21:49 2008''
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Current revision

CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA

PDB ID 238d

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