272d

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[[Image:272d.jpg|left|200px]]
 
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==PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE==
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The line below this paragraph, containing "STRUCTURE_272d", creates the "Structure Box" on the page.
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<StructureSection load='272d' size='340' side='right'caption='[[272d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[272d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=272D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=272D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=272d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=272d OCA], [https://pdbe.org/272d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=272d RCSB], [https://www.ebi.ac.uk/pdbsum/272d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=272d ProSAT]</span></td></tr>
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{{STRUCTURE_272d| PDB=272d | SCENE= }}
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</table>
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__TOC__
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'''PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE'''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Dautant A]]
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==Overview==
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[[Category: Gallois B]]
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Nucleic acid triplexes are formed by sequence-specific interactions between single-stranded polynucleotides and the double helix. These triplexes are implicated in genetic recombination in vivo and have application to areas that include genome analysis and antigene therapy. Despite the importance of the triple helix, only limited high-resolution structural information is available. The x-ray crystal structure of the oligonucleotide d(GGCCAATTGG) is described; it was designed to contain the d(G middle dotGC)2 fragment and thus provide the basic repeat unit of a DNA triple helix. Parameters derived from this crystal structure have made it possible to construct models of both parallel and antiparallel triple helices.
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[[Category: Kennard O]]
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[[Category: Precigoux G]]
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==About this Structure==
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[[Category: Van Meervelt L]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=272D OCA].
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[[Category: Vlieghe D]]
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==Reference==
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Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure., Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O, Science. 1996 Sep 20;273(5282):1702-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8781231 8781231]
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[[Category: Dautant, A.]]
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[[Category: Gallois, B.]]
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[[Category: Kennard, O.]]
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[[Category: Meervelt, L Van.]]
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[[Category: Precigoux, G.]]
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[[Category: Vlieghe, D.]]
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[[Category: B-dna]]
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[[Category: Double helix]]
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[[Category: Intermolecular base triplet]]
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[[Category: Overhanging base]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:24:59 2008''
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Current revision

PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE

PDB ID 272d

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