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2ak7

From Proteopedia

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[[Image:2ak7.gif|left|200px]]
 
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==structure of a dimeric P-Ser-Crh==
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The line below this paragraph, containing "STRUCTURE_2ak7", creates the "Structure Box" on the page.
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<StructureSection load='2ak7' size='340' side='right'caption='[[2ak7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ak7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AK7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2ak7| PDB=2ak7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ak7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ak7 OCA], [https://pdbe.org/2ak7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ak7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ak7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ak7 ProSAT]</span></td></tr>
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</table>
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'''structure of a dimeric P-Ser-Crh'''
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== Function ==
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[https://www.uniprot.org/uniprot/CRH_BACSU CRH_BACSU] Along with seryl-phosphorylated HPr, phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase, inositol dehydrogenase, and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA.<ref>PMID:9237995</ref> <ref>PMID:16316990</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2AK7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AK7 OCA].
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Check<jmol>
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<jmolCheckbox>
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==Reference==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ak/2ak7_consurf.spt"</scriptWhenChecked>
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X-ray structure of a domain-swapped dimer of Ser46-phosphorylated Crh from Bacillus subtilis., Chaptal V, Lariviere L, Gueguen-Chaignon V, Galinier A, Nessler S, Morera S, Proteins. 2006 Apr 1;63(1):249-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16411239 16411239]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ak7 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Chaptal, V.]]
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[[Category: Chaptal V]]
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[[Category: Deutscher, J.]]
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[[Category: Deutscher J]]
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[[Category: Galinier, A.]]
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[[Category: Galinier A]]
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[[Category: Gueguen-Chaignon, V.]]
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[[Category: Gueguen-Chaignon V]]
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[[Category: Lariviere, L.]]
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[[Category: Lariviere L]]
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[[Category: Lecampion, C.]]
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[[Category: Lecampion C]]
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[[Category: Meyer, P.]]
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[[Category: Meyer P]]
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[[Category: Morera, S.]]
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[[Category: Morera S]]
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[[Category: Nessler, S.]]
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[[Category: Nessler S]]
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[[Category: Poncet, S.]]
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[[Category: Poncet S]]
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[[Category: Crh]]
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[[Category: P-crh]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:09:05 2008''
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Current revision

structure of a dimeric P-Ser-Crh

PDB ID 2ak7

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