2fvz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /> <applet load="2fvz" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fvz, resolution 2.400&Aring;" /> '''Human Inositol Mon...)
Current revision (07:53, 23 October 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2fvz.gif|left|200px]]<br />
 
-
<applet load="2fvz" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2fvz, resolution 2.400&Aring;" />
 
-
'''Human Inositol Monophosphosphatase 2'''<br />
 
-
==About this Structure==
+
==Human Inositol Monophosphosphatase 2==
-
2FVZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Inositol-phosphate_phosphatase Inositol-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.25 3.1.3.25] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2FVZ OCA].
+
<StructureSection load='2fvz' size='340' side='right'caption='[[2fvz]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
[[Category: Homo sapiens]]
+
== Structural highlights ==
-
[[Category: Inositol-phosphate phosphatase]]
+
<table><tr><td colspan='2'>[[2fvz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FVZ FirstGlance]. <br>
-
[[Category: Single protein]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
[[Category: Arrowsmith, C.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fvz OCA], [https://pdbe.org/2fvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fvz RCSB], [https://www.ebi.ac.uk/pdbsum/2fvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fvz ProSAT]</span></td></tr>
-
[[Category: Berg, S.Van.Den.]]
+
</table>
-
[[Category: Berglund, H.]]
+
== Function ==
-
[[Category: Collins, R.]]
+
[https://www.uniprot.org/uniprot/IMPA2_HUMAN IMPA2_HUMAN] Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain.<ref>PMID:17068342</ref>
-
[[Category: Edwards, A.]]
+
== Evolutionary Conservation ==
-
[[Category: Ehn, M.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Flodin, S.]]
+
Check<jmol>
-
[[Category: Graslund, S.]]
+
<jmolCheckbox>
-
[[Category: Hallberg, B.M.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/2fvz_consurf.spt"</scriptWhenChecked>
-
[[Category: Hammarstrom, M.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
-
[[Category: Hogbom, M.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Holmberg-Schiavone, L.]]
+
</jmolCheckbox>
-
[[Category: Kotenyova, T.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fvz ConSurf].
-
[[Category: Kursula, P.]]
+
<div style="clear:both"></div>
-
[[Category: Nilsson-Ehle, P.]]
+
-
[[Category: Nordlund, P.]]
+
-
[[Category: Nyman, T.]]
+
-
[[Category: Ogg, D.]]
+
-
[[Category: Persson, C.]]
+
-
[[Category: SGC, Structural.Genomics.Consortium.]]
+
-
[[Category: Sagemark, J.]]
+
-
[[Category: Stenmark, P.]]
+
-
[[Category: Sundstrom, M.]]
+
-
[[Category: Thorsell, A.G.]]
+
-
[[Category: Weigelt, J.]]
+
-
[[Category: inositol metabolism]]
+
-
[[Category: inositol monophosphatase]]
+
-
[[Category: sgc]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural genomics consortium]]
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 22:11:10 2007''
+
==See Also==
 +
*[[Inositol monophosphatase 3D structures|Inositol monophosphatase 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Arrowsmith C]]
 +
[[Category: Berglund H]]
 +
[[Category: Collins R]]
 +
[[Category: Edwards A]]
 +
[[Category: Ehn M]]
 +
[[Category: Flodin S]]
 +
[[Category: Graslund S]]
 +
[[Category: Hallberg BM]]
 +
[[Category: Hammarstrom M]]
 +
[[Category: Hogbom M]]
 +
[[Category: Holmberg-Schiavone L]]
 +
[[Category: Kotenyova T]]
 +
[[Category: Kursula P]]
 +
[[Category: Nilsson-Ehle P]]
 +
[[Category: Nordlund P]]
 +
[[Category: Nyman T]]
 +
[[Category: Ogg D]]
 +
[[Category: Persson C]]
 +
[[Category: Sagemark J]]
 +
[[Category: Stenmark P]]
 +
[[Category: Sundstrom M]]
 +
[[Category: Thorsell AG]]
 +
[[Category: Van Den Berg S]]
 +
[[Category: Weigelt J]]

Current revision

Human Inositol Monophosphosphatase 2

PDB ID 2fvz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2fvz"
Personal tools