2g3y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /> <applet load="2g3y" size="450" color="white" frame="true" align="right" spinBox="true" caption="2g3y, resolution 2.40&Aring;" /> '''Crystal structure o...)
Current revision (09:35, 30 August 2023) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2g3y.gif|left|200px]]<br />
 
-
<applet load="2g3y" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2g3y, resolution 2.40&Aring;" />
 
-
'''Crystal structure of the human small GTPase GEM'''<br />
 
-
==Disease==
+
==Crystal structure of the human small GTPase GEM==
-
Known diseases associated with this structure: Long QT syndrome-7 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600681 600681]], Short QT syndrome-3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600681 600681]]
+
<StructureSection load='2g3y' size='340' side='right'caption='[[2g3y]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2g3y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3Y FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3y OCA], [https://pdbe.org/2g3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3y RCSB], [https://www.ebi.ac.uk/pdbsum/2g3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3y ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/GEM_HUMAN GEM_HUMAN] Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g3y_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g3y ConSurf].
 +
<div style="clear:both"></div>
-
==About this Structure==
+
==See Also==
-
2G3Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with GDP as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2G3Y OCA].
+
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Berridge, G.]]
+
[[Category: Berridge G]]
-
[[Category: Bray, J.]]
+
[[Category: Bray J]]
-
[[Category: Burgess, N.]]
+
[[Category: Burgess N]]
-
[[Category: Delft, F.von.]]
+
[[Category: Doyle D]]
-
[[Category: Doyle, D.]]
+
[[Category: Edwards A]]
-
[[Category: Edwards, A.]]
+
[[Category: Elkins J]]
-
[[Category: Elkins, J.]]
+
[[Category: Fedorov O]]
-
[[Category: Fedorov, O.]]
+
[[Category: Gileadi C]]
-
[[Category: Gileadi, C.]]
+
[[Category: Lee WH]]
-
[[Category: Lee, W.H.]]
+
[[Category: Pantic N]]
-
[[Category: Pantic, N.]]
+
[[Category: Schoch G]]
-
[[Category: SGC, Structural.Genomics.Consortium.]]
+
[[Category: Sobott F]]
-
[[Category: Schoch, G.]]
+
[[Category: Soundararajan M]]
-
[[Category: Sobott, F.]]
+
[[Category: Sundstrom M]]
-
[[Category: Soundararajan, M.]]
+
[[Category: Turnbull A]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Ugochukwu E]]
-
[[Category: Turnbull, A.]]
+
[[Category: Weigelt J]]
-
[[Category: Ugochukwu, E.]]
+
[[Category: Von Delft F]]
-
[[Category: Weigelt, J.]]
+
-
[[Category: GDP]]
+
-
[[Category: gdp]]
+
-
[[Category: gem]]
+
-
[[Category: inactive state]]
+
-
[[Category: rgk family]]
+
-
[[Category: sgc]]
+
-
[[Category: small gtpase]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural genomics consortium]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 22:14:10 2007''
+

Current revision

Crystal structure of the human small GTPase GEM

PDB ID 2g3y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2g3y"
Personal tools