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2gf0
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2gf0" size="450" color="white" frame="true" align="right" spinBox="true" caption="2gf0, resolution 1.90Å" /> '''The crystal structu...) |
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| - | [[Image:2gf0.gif|left|200px]]<br /> | ||
| - | <applet load="2gf0" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2gf0, resolution 1.90Å" /> | ||
| - | '''The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state'''<br /> | ||
| - | == | + | ==The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state== |
| - | + | <StructureSection load='2gf0' size='340' side='right'caption='[[2gf0]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [https://pdbe.org/2gf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DIRA1_HUMAN DIRA1_HUMAN] Displays low GTPase activity and exist predominantly in the GTP-bound form. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf0 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]] | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith C]] |
| - | [[Category: Bray | + | [[Category: Bray J]] |
| - | + | [[Category: Doyle D]] | |
| - | [[Category: Doyle | + | [[Category: Edwards A]] |
| - | [[Category: Edwards | + | [[Category: Elkins J]] |
| - | [[Category: Elkins | + | [[Category: Fedorov O]] |
| - | [[Category: Fedorov | + | [[Category: Gileadi O]] |
| - | [[Category: Gileadi | + | [[Category: Niesen FE]] |
| - | [[Category: Niesen | + | [[Category: Papagrigoriou E]] |
| - | [[Category: Papagrigoriou | + | [[Category: Salah E]] |
| - | + | [[Category: Schoch G]] | |
| - | [[Category: Salah | + | [[Category: Sundstrom M]] |
| - | [[Category: Schoch | + | [[Category: Turnbull AP]] |
| - | [[Category: Sundstrom | + | [[Category: Weigelt J]] |
| - | [[Category: Turnbull | + | [[Category: Wen-Hwa L]] |
| - | [[Category: Weigelt | + | [[Category: Yang X]] |
| - | [[Category: Wen-Hwa | + | [[Category: Von Delft F]] |
| - | [[Category: Yang | + | |
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Current revision
The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Bray J | Doyle D | Edwards A | Elkins J | Fedorov O | Gileadi O | Niesen FE | Papagrigoriou E | Salah E | Schoch G | Sundstrom M | Turnbull AP | Weigelt J | Wen-Hwa L | Yang X | Von Delft F
