2d9l

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[[Image:2d9l.gif|left|200px]]
 
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==Solution structure of the ArfGap domain of human RIP==
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The line below this paragraph, containing "STRUCTURE_2d9l", creates the "Structure Box" on the page.
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<StructureSection load='2d9l' size='340' side='right'caption='[[2d9l]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2d9l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D9L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2d9l| PDB=2d9l | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d9l OCA], [https://pdbe.org/2d9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d9l RCSB], [https://www.ebi.ac.uk/pdbsum/2d9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d9l ProSAT], [https://www.topsan.org/Proteins/RSGI/2d9l TOPSAN]</span></td></tr>
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</table>
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'''Solution structure of the ArfGap domain of human RIP'''
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== Function ==
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[https://www.uniprot.org/uniprot/AGFG1_HUMAN AGFG1_HUMAN] Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.<ref>PMID:10613896</ref> <ref>PMID:14701878</ref> <ref>PMID:15749819</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2D9L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9L OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/2d9l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d9l ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi F]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Suetake T]]
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[[Category: Suetake, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Arfgap domain]]
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[[Category: Hiv-1]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rev]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rip]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Zinc finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 23:57:09 2008''
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Current revision

Solution structure of the ArfGap domain of human RIP

PDB ID 2d9l

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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