2ddi

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[[Image:2ddi.jpg|left|200px]]
 
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==NMR structure of the second Kunitz domain of human WFIKKN1==
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The line below this paragraph, containing "STRUCTURE_2ddi", creates the "Structure Box" on the page.
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<StructureSection load='2ddi' size='340' side='right'caption='[[2ddi]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ddi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ddi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ddi OCA], [https://pdbe.org/2ddi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ddi RCSB], [https://www.ebi.ac.uk/pdbsum/2ddi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ddi ProSAT]</span></td></tr>
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{{STRUCTURE_2ddi| PDB=2ddi | SCENE= }}
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</table>
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== Function ==
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'''NMR structure of the second Kunitz domain of human WFIKKN1'''
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[https://www.uniprot.org/uniprot/WFKN1_HUMAN WFKN1_HUMAN] Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2DDI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDI OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dd/2ddi_consurf.spt"</scriptWhenChecked>
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==Reference==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein., Liepinsh E, Nagy A, Trexler M, Patthy L, Otting G, J Biomol NMR. 2006 May;35(1):73-8. Epub 2006 Jun 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16791741 16791741]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ddi ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Liepinsh, E.]]
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[[Category: Liepinsh E]]
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[[Category: Otting, G.]]
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[[Category: Otting G]]
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[[Category: Kunitz domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 00:13:31 2008''
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Current revision

NMR structure of the second Kunitz domain of human WFIKKN1

PDB ID 2ddi

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OCA

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