2djw

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[[Image:2djw.gif|left|200px]]
 
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==Crystal structure of TTHA0845 from Thermus thermophilus HB8==
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The line below this paragraph, containing "STRUCTURE_2djw", creates the "Structure Box" on the page.
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<StructureSection load='2djw' size='340' side='right'caption='[[2djw]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2djw]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DJW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2djw| PDB=2djw | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2djw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2djw OCA], [https://pdbe.org/2djw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2djw RCSB], [https://www.ebi.ac.uk/pdbsum/2djw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2djw ProSAT], [https://www.topsan.org/Proteins/RSGI/2djw TOPSAN]</span></td></tr>
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</table>
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'''Crystal structure of TTHA0845 from Thermus thermophilus HB8'''
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SK07_THET8 Q5SK07_THET8]
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== Evolutionary Conservation ==
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==Overview==
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[[Image:Consurf_key_small.gif|200px|right]]
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The stand-alone RAM (regulation of amino-acid metabolism) domain protein SraA from Thermus thermophilus HB8 (TTHA0845) was crystallized in the presence of zinc ions. The X-ray crystal structure was determined using a multiple-wavelength anomalous dispersion technique and was refined at 2.4 A resolution to a final R factor of 25.0%. The monomeric structure is a betaalphabetabetaalphabeta fold and it dimerizes mainly through interactions between the antiparallel beta-sheets. Furthermore, five SraA dimers form a ring with external and internal diameters of 70 and 20 A, respectively. This decameric structure is unique compared with the octameric and dodecameric structures found for other stand-alone RAM-domain proteins and the C-terminal RAM domains of Lrp/AsnC-family proteins.
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dj/2djw_consurf.spt"</scriptWhenChecked>
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2DJW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DJW OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Structure of the stand-alone RAM-domain protein from Thermus thermophilus HB8., Nakano N, Okazaki N, Satoh S, Takio K, Kuramitsu S, Shinkai A, Yokoyama S, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt, 9):855-60. Epub 2006 Aug 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16946463 16946463]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2djw ConSurf].
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[[Category: Single protein]]
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<div style="clear:both"></div>
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[[Category: Thermus thermophilus]]
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__TOC__
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[[Category: Nakano, N.]]
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</StructureSection>
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[[Category: Okazaki, N.]]
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[[Category: Large Structures]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Shinkai, A.]]
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[[Category: Nakano N]]
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[[Category: Yokoyama, S.]]
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[[Category: Okazaki N]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Shinkai A]]
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[[Category: Nppsfa]]
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[[Category: Yokoyama S]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Thermus thermophilus hb8]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 00:34:31 2008''
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Current revision

Crystal structure of TTHA0845 from Thermus thermophilus HB8

PDB ID 2djw

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