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2dvx

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[[Image:2dvx.gif|left|200px]]
 
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==Crystal Structure of 2,6-Dihydroxybenzoate Decarboxylase Complexed with inhibitor 2,3-dihydroxybenzaldehyde==
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The line below this paragraph, containing "STRUCTURE_2dvx", creates the "Structure Box" on the page.
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<StructureSection load='2dvx' size='340' side='right'caption='[[2dvx]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2dvx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizobium_sp._MTP-10005 Rhizobium sp. MTP-10005]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DVX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23A:2,3-DIHYDROXYBENZALDEHYDE'>23A</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2dvx| PDB=2dvx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dvx OCA], [https://pdbe.org/2dvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dvx RCSB], [https://www.ebi.ac.uk/pdbsum/2dvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dvx ProSAT]</span></td></tr>
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</table>
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'''Crystal Structure of 2,6-Dihydroxybenzoate Decarboxylase Complexed with inhibitor 2,3-dihydroxybenzaldehyde'''
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== Function ==
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[https://www.uniprot.org/uniprot/GRDC_RHIS5 GRDC_RHIS5] Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (PubMed:15466039). Catalyzes the reversible decarboxylation of gamma-resorcylate to resorcinol (PubMed:15466039). The reaction is reversible, but equilibrium greatly favors the decarboxylation reaction (PubMed:15466039). Also catalyzes the decarboxylation of 2,3-dihydroxybenzoate to catechol, but does not act on 2,4-dihydroxybenzoate, 2,5-dihydroxybenzoate, 3,4-dihydroxybenzoate, 3,5-dihydroxybenzoate, 2-hydroxybenzoate, or 3-hydroxybenzoate. Only resorcinol is carboxylated by the reverse reaction (PubMed:15466039).<ref>PMID:15466039</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2DVX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhizobium_sp. Rhizobium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DVX OCA].
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Check<jmol>
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[[Category: Rhizobium sp.]]
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<jmolCheckbox>
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[[Category: Single protein]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dv/2dvx_consurf.spt"</scriptWhenChecked>
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[[Category: Goto, M.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Tim barrel]]
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<text>to colour the structure by Evolutionary Conservation</text>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 01:29:27 2008''
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dvx ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Rhizobium sp. MTP-10005]]
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[[Category: Goto M]]

Current revision

Crystal Structure of 2,6-Dihydroxybenzoate Decarboxylase Complexed with inhibitor 2,3-dihydroxybenzaldehyde

PDB ID 2dvx

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