This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2he7
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2he7" size="450" color="white" frame="true" align="right" spinBox="true" caption="2he7, resolution 2.000Å" /> '''FERM domain of EPB...) |
|||
| (14 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2he7.gif|left|200px]]<br /> | ||
| - | <applet load="2he7" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2he7, resolution 2.000Å" /> | ||
| - | '''FERM domain of EPB41L3 (DAL-1)'''<br /> | ||
| - | == | + | ==FERM domain of EPB41L3 (DAL-1)== |
| - | + | <StructureSection load='2he7' size='340' side='right'caption='[[2he7]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2he7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HE7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2he7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2he7 OCA], [https://pdbe.org/2he7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2he7 RCSB], [https://www.ebi.ac.uk/pdbsum/2he7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2he7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/E41L3_HUMAN E41L3_HUMAN] Critical growth regulator in the pathogenesis of meningiomas. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/he/2he7_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2he7 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith C]] |
| - | [[Category: Berglund | + | [[Category: Berglund H]] |
| - | [[Category: Busam | + | [[Category: Busam RD]] |
| - | [[Category: Collins | + | [[Category: Collins R]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Ehn | + | [[Category: Ehn M]] |
| - | [[Category: Flodin | + | [[Category: Flodin S]] |
| - | [[Category: Flores | + | [[Category: Flores A]] |
| - | [[Category: Graslund | + | [[Category: Graslund S]] |
| - | [[Category: Hallberg | + | [[Category: Hallberg BM]] |
| - | [[Category: Hammarstrom | + | [[Category: Hammarstrom M]] |
| - | [[Category: Hogbom | + | [[Category: Hogbom M]] |
| - | [[Category: Johansson | + | [[Category: Johansson I]] |
| - | [[Category: Karlberg | + | [[Category: Karlberg T]] |
| - | [[Category: Kotenyova | + | [[Category: Kotenyova T]] |
| - | [[Category: Nilsson-ehle | + | [[Category: Nilsson-ehle P]] |
| - | [[Category: Nilvebrandt | + | [[Category: Nilvebrandt J]] |
| - | [[Category: Norberg | + | [[Category: Norberg P]] |
| - | [[Category: Nordlund | + | [[Category: Nordlund P]] |
| - | [[Category: Nyman | + | [[Category: Nyman T]] |
| - | [[Category: Ogg | + | [[Category: Ogg D]] |
| - | [[Category: Persson | + | [[Category: Persson C]] |
| - | + | [[Category: Sagemark J]] | |
| - | [[Category: Sagemark | + | [[Category: Schiavone LH]] |
| - | [[Category: Schiavone | + | [[Category: Stenmark P]] |
| - | [[Category: Stenmark | + | [[Category: Sundstrom M]] |
| - | [[Category: Sundstrom | + | [[Category: Thorsell AG]] |
| - | [[Category: Thorsell | + | [[Category: Uppenberg J]] |
| - | [[Category: Uppenberg | + | [[Category: Van den berg S]] |
| - | + | [[Category: Weigelt J]] | |
| - | [[Category: berg | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
FERM domain of EPB41L3 (DAL-1)
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith C | Berglund H | Busam RD | Collins R | Edwards A | Ehn M | Flodin S | Flores A | Graslund S | Hallberg BM | Hammarstrom M | Hogbom M | Johansson I | Karlberg T | Kotenyova T | Nilsson-ehle P | Nilvebrandt J | Norberg P | Nordlund P | Nyman T | Ogg D | Persson C | Sagemark J | Schiavone LH | Stenmark P | Sundstrom M | Thorsell AG | Uppenberg J | Van den berg S | Weigelt J
