This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2fu4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:51, 13 March 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2fu4.gif|left|200px]]
 
-
<!--
+
==Crystal Structure of the DNA binding domain of E.coli FUR (Ferric Uptake Regulator)==
-
The line below this paragraph, containing "STRUCTURE_2fu4", creates the "Structure Box" on the page.
+
<StructureSection load='2fu4' size='340' side='right'caption='[[2fu4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2fu4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FU4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FU4 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
{{STRUCTURE_2fu4| PDB=2fu4 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fu4 OCA], [https://pdbe.org/2fu4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fu4 RCSB], [https://www.ebi.ac.uk/pdbsum/2fu4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fu4 ProSAT]</span></td></tr>
-
 
+
</table>
-
'''Crystal Structure of the DNA binding domain of E.coli FUR (Ferric Uptake Regulator)'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/FUR_ECOLI FUR_ECOLI] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon.<ref>PMID:2823881</ref>
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2FU4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FU4 OCA].
+
Check<jmol>
-
[[Category: Escherichia coli]]
+
<jmolCheckbox>
-
[[Category: Single protein]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/2fu4_consurf.spt"</scriptWhenChecked>
-
[[Category: Autreaux, B D.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Bersch, B.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Brutscher, B.]]
+
</jmolCheckbox>
-
[[Category: Dupuy, J.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fu4 ConSurf].
-
[[Category: Jacquamet, L.]]
+
<div style="clear:both"></div>
-
[[Category: Michaud-Soret, I.]]
+
== References ==
-
[[Category: Nicolet, Y.]]
+
<references/>
-
[[Category: Pecqueur, L.]]
+
__TOC__
-
[[Category: Dna binding domain]]
+
</StructureSection>
-
[[Category: Helix-turn-helix]]
+
[[Category: Escherichia coli BL21]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:18:33 2008''
+
[[Category: Large Structures]]
 +
[[Category: Bersch B]]
 +
[[Category: Brutscher B]]
 +
[[Category: D'Autreaux B]]
 +
[[Category: Dupuy J]]
 +
[[Category: Jacquamet L]]
 +
[[Category: Michaud-Soret I]]
 +
[[Category: Nicolet Y]]
 +
[[Category: Pecqueur L]]

Current revision

Crystal Structure of the DNA binding domain of E.coli FUR (Ferric Uptake Regulator)

PDB ID 2fu4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2fu4"
Personal tools