2g1w

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[[Image:2g1w.gif|left|200px]]
 
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==NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1==
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The line below this paragraph, containing "STRUCTURE_2g1w", creates the "Structure Box" on the page.
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<StructureSection load='2g1w' size='340' side='right'caption='[[2g1w]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2g1w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G1W FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g1w OCA], [https://pdbe.org/2g1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g1w RCSB], [https://www.ebi.ac.uk/pdbsum/2g1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g1w ProSAT]</span></td></tr>
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{{STRUCTURE_2g1w| PDB=2g1w | SCENE= }}
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</table>
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<div style="background-color:#fffaf0;">
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'''NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1'''
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== Publication Abstract from PubMed ==
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==Overview==
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The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.
The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.
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==About this Structure==
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NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation.,Nonin-Lecomte S, Felden B, Dardel F Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798<ref>PMID:16595798</ref>
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16595798 16595798]
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</div>
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[[Category: Dardel, F.]]
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<div class="pdbe-citations 2g1w" style="background-color:#fffaf0;"></div>
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[[Category: Nonin-Lecomte, S.]]
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== References ==
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[[Category: Nmr]]
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<references/>
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[[Category: Pk1]]
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__TOC__
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[[Category: Pseudoknot]]
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</StructureSection>
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[[Category: Tmrna]]
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[[Category: Large Structures]]
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[[Category: Trans-translation]]
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[[Category: Dardel F]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:36:13 2008''
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[[Category: Nonin-Lecomte S]]

Current revision

NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1

PDB ID 2g1w

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