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2g3v

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[[Image:2g3v.gif|left|200px]]
 
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==Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori==
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The line below this paragraph, containing "STRUCTURE_2g3v", creates the "Structure Box" on the page.
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<StructureSection load='2g3v' size='340' side='right'caption='[[2g3v]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2g3v]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3v OCA], [https://pdbe.org/2g3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3v RCSB], [https://www.ebi.ac.uk/pdbsum/2g3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3v ProSAT]</span></td></tr>
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{{STRUCTURE_2g3v| PDB=2g3v | SCENE= }}
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</table>
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== Function ==
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'''Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori'''
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[https://www.uniprot.org/uniprot/CAGS_HELPY CAGS_HELPY]
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__TOC__
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</StructureSection>
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==Overview==
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CagZ, a 23 kDa protein encoded by the cagZ gene (HP0526) of the cag pathogenicity island of Helicobacter pylori, has been cloned, over-expressed, purified and its three-dimensional structure determined. The protein consists of a single compact L-shaped domain, composed of seven alpha-helices including about 70% of the total residues. Three-dimensional homology searches did not reveal structural homologues, and CagZ can be considered representative of a new protein fold. The presence of a disordered C-terminal tail and the nature of the molecular surface suggest that CagZ may participate in the interaction of effector proteins with one or more components of the H.pylori type IV secretion system on the cytoplasmic side of the inner membrane.
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==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA].
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==Reference==
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Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system., Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G, J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15223328 15223328]
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[[Category: Angelini, A.]]
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[[Category: Battistutta, R.]]
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[[Category: Cendron, L.]]
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[[Category: Montecucco, C.]]
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[[Category: Seydel, A.]]
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[[Category: Tasca, E.]]
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[[Category: Zanotti, G.]]
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[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Pathogenicity island]]
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[[Category: Large Structures]]
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[[Category: Type iv secretion system]]
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[[Category: Angelini A]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:39:39 2008''
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[[Category: Battistutta R]]
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[[Category: Cendron L]]
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[[Category: Montecucco C]]
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[[Category: Seydel A]]
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[[Category: Tasca E]]
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[[Category: Zanotti G]]

Current revision

Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori

PDB ID 2g3v

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