2g4s

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[[Image:2g4s.gif|left|200px]]
 
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==Anomalous substructure of NBR1PB1==
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The line below this paragraph, containing "STRUCTURE_2g4s", creates the "Structure Box" on the page.
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<StructureSection load='2g4s' size='340' side='right'caption='[[2g4s]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2g4s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G4S FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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{{STRUCTURE_2g4s| PDB=2g4s | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g4s OCA], [https://pdbe.org/2g4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g4s RCSB], [https://www.ebi.ac.uk/pdbsum/2g4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g4s ProSAT]</span></td></tr>
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</table>
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'''Anomalous substructure of NBR1PB1'''
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== Function ==
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[https://www.uniprot.org/uniprot/NBR1_HUMAN NBR1_HUMAN] Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.<ref>PMID:19250911</ref>
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== References ==
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==Overview==
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<references/>
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23 different crystal forms of 19 different biological macromolecules were examined with respect to their anomalously scattering substructures using diffraction data collected at a wavelength of 2.0 A (6.2 keV). In more than 90% of the cases the substructure was found to contain more than just the protein S atoms. The data presented suggest that chloride, sulfate, phosphate or metal ions from the buffer or even from the purification protocol are frequently bound to the protein molecule and that these ions are often overlooked, especially if they are not bound at full occupancy. Thus, in order to fully describe the macromolecule under study, it seems desirable that any structure determination be complemented with a long-wavelength data set.
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__TOC__
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</StructureSection>
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==About this Structure==
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2G4S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G4S OCA].
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==Reference==
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On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths., Mueller-Dieckmann C, Panjikar S, Schmidt A, Mueller S, Kuper J, Geerlof A, Wilmanns M, Singh RK, Tucker PA, Weiss MS, Acta Crystallogr D Biol Crystallogr. 2007 Mar;63(Pt 3):366-80. Epub 2007, Feb 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17327674 17327674]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Mueller-Dieckmann, C.]]
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[[Category: Mueller-Dieckmann C]]
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[[Category: Weiss, M S.]]
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[[Category: Weiss MS]]
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[[Category: Anomalous substructure of nbr1pb1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:41:23 2008''
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Current revision

Anomalous substructure of NBR1PB1

PDB ID 2g4s

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