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2g6z

From Proteopedia

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[[Image:2g6z.jpg|left|200px]]
 
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==Crystal structure of human DUSP5==
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The line below this paragraph, containing "STRUCTURE_2g6z", creates the "Structure Box" on the page.
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<StructureSection load='2g6z' size='340' side='right'caption='[[2g6z]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2g6z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G6Z FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6z OCA], [https://pdbe.org/2g6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g6z RCSB], [https://www.ebi.ac.uk/pdbsum/2g6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g6z ProSAT]</span></td></tr>
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{{STRUCTURE_2g6z| PDB=2g6z | SCENE= }}
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/DUS5_HUMAN DUS5_HUMAN]] Displays phosphatase activity toward several substrates. The highest relative activity is toward ERK1.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/2g6z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g6z ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of human DUSP5'''
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==See Also==
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*[[MAP kinase phosphatase|MAP kinase phosphatase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2G6Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6Z OCA].
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[[Category: Human]]
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[[Category: Large Structures]]
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==Reference==
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[[Category: Kim, S J]]
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Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase., Jeong DG, Cho YH, Yoon TS, Kim JH, Ryu SE, Kim SJ, Proteins. 2007 Jan 1;66(1):253-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17078075 17078075]
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[[Category: Ryu, S E]]
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[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Kim, S J.]]
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[[Category: Ryu, S E.]]
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[[Category: Alpha/beta]]
[[Category: Alpha/beta]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:45:37 2008''
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[[Category: Hydrolase]]

Current revision

Crystal structure of human DUSP5

PDB ID 2g6z

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OCA

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