This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2o52
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2o52" size="450" color="white" frame="true" align="right" spinBox="true" caption="2o52, resolution 2.200Å" /> '''Crystal structure ...) |
|||
| (14 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2o52.gif|left|200px]]<br /> | ||
| - | <applet load="2o52" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2o52, resolution 2.200Å" /> | ||
| - | '''Crystal structure of human RAB4B in complex with GDP'''<br /> | ||
| - | == | + | ==Crystal structure of human RAB4B in complex with GDP== |
| - | + | <StructureSection load='2o52' size='340' side='right'caption='[[2o52]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2o52]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O52 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o52 OCA], [https://pdbe.org/2o52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o52 RCSB], [https://www.ebi.ac.uk/pdbsum/2o52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o52 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [ | + | [https://www.uniprot.org/uniprot/RAB4B_HUMAN RAB4B_HUMAN] Protein transport. Probably involved in vesicular traffic (By similarity). |
| - | [ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o52_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | [[ | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o52 ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | + | ||
| - | + | ||
| - | [ | + | |
| - | [[ | + | |
| - | [ | + | |
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bochkarev A]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Landry R]] | ||
| + | [[Category: Park H]] | ||
| + | [[Category: Shen Y]] | ||
| + | [[Category: Sundstrom M]] | ||
| + | [[Category: Tempel W]] | ||
| + | [[Category: Wang J]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Zhu H]] | ||
Current revision
Crystal structure of human RAB4B in complex with GDP
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Edwards AM | Landry R | Park H | Shen Y | Sundstrom M | Tempel W | Wang J | Weigelt J | Zhu H
