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2oy2
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2oy2" size="450" color="white" frame="true" align="right" spinBox="true" caption="2oy2, resolution 1.50Å" /> '''Human MMP-8 in comp...) |
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| - | [[Image:2oy2.gif|left|200px]]<br /> | ||
| - | <applet load="2oy2" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2oy2, resolution 1.50Å" /> | ||
| - | '''Human MMP-8 in complex with peptide IAG'''<br /> | ||
| - | == | + | ==Human MMP-8 in complex with peptide IAG== |
| - | + | <StructureSection load='2oy2' size='340' side='right'caption='[[2oy2]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2oy2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OY2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oy2 OCA], [https://pdbe.org/2oy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oy2 RCSB], [https://www.ebi.ac.uk/pdbsum/2oy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oy2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN] Can degrade fibrillar type I, II, and III collagens. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/2oy2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oy2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]] | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | + | [[Category: Bertini I]] | |
| - | [[Category: Bertini | + | [[Category: Calderone V]] |
| - | [[Category: Calderone | + | [[Category: Fragai M]] |
| - | [[Category: Fragai | + | [[Category: Luchinat C]] |
| - | [[Category: Luchinat | + | [[Category: Maletta M]] |
| - | [[Category: Maletta | + | [[Category: Yeo KJ]] |
| - | [[Category: Yeo | + | |
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Current revision
Human MMP-8 in complex with peptide IAG
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Categories: Homo sapiens | Large Structures | Bertini I | Calderone V | Fragai M | Luchinat C | Maletta M | Yeo KJ
