2p0a

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(New page: 200px<br /> <applet load="2p0a" size="450" color="white" frame="true" align="right" spinBox="true" caption="2p0a, resolution 1.90&Aring;" /> '''The crystal structu...)
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[[Image:2p0a.gif|left|200px]]<br />
 
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<applet load="2p0a" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2p0a, resolution 1.90&Aring;" />
 
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'''The crystal structure of human synapsin III (SYN3) in complex with AMPPNP'''<br />
 
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==About this Structure==
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==The crystal structure of human synapsin III (SYN3) in complex with AMPPNP==
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2P0A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CL, SO4, ANP and EDO as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2P0A OCA].
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<StructureSection load='2p0a' size='340' side='right'caption='[[2p0a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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[[Category: Homo sapiens]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2p0a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P0A FirstGlance]. <br>
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[[Category: Arrowsmith, C.H.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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[[Category: Burgess, N.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Delft, F.von.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0a OCA], [https://pdbe.org/2p0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p0a RCSB], [https://www.ebi.ac.uk/pdbsum/2p0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p0a ProSAT]</span></td></tr>
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[[Category: Doyle, D.]]
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</table>
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[[Category: Edwards, A.]]
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== Function ==
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[[Category: Elkins, J.M.]]
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[https://www.uniprot.org/uniprot/SYN3_HUMAN SYN3_HUMAN] May be involved in the regulation of neurotransmitter release and synaptogenesis.
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[[Category: Gileadi, C.]]
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== Evolutionary Conservation ==
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[[Category: Gileadi, O.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Gorrec, F.]]
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Check<jmol>
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[[Category: Niesen, F.H.]]
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<jmolCheckbox>
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[[Category: Phillips, C.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/2p0a_consurf.spt"</scriptWhenChecked>
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[[Category: Pike, A.C.W.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: SGC, Structural.Genomics.Consortium.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Salah, E.]]
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</jmolCheckbox>
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[[Category: Sundstrom, M.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p0a ConSurf].
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[[Category: Turnbull, A.P.]]
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<div style="clear:both"></div>
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[[Category: Umeano, C.]]
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[[Category: Weigelt, J.]]
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[[Category: ANP]]
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[[Category: CL]]
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[[Category: EDO]]
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[[Category: SO4]]
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[[Category: neurotransmitter release]]
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[[Category: schizophrenia]]
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[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomics consortium]]
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[[Category: synapsin]]
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[[Category: vesicle transport ]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:18:54 2007''
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==See Also==
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*[[Synapsin|Synapsin]]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Burgess N]]
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[[Category: Doyle D]]
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[[Category: Edwards A]]
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[[Category: Elkins JM]]
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[[Category: Gileadi C]]
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[[Category: Gileadi O]]
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[[Category: Gorrec F]]
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[[Category: Niesen FH]]
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[[Category: Phillips C]]
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[[Category: Pike ACW]]
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[[Category: Salah E]]
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[[Category: Sundstrom M]]
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[[Category: Turnbull AP]]
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[[Category: Umeano C]]
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[[Category: Weigelt J]]
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[[Category: Von Delft F]]

Current revision

The crystal structure of human synapsin III (SYN3) in complex with AMPPNP

PDB ID 2p0a

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