2p5s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /> <applet load="2p5s" size="450" color="white" frame="true" align="right" spinBox="true" caption="2p5s, resolution 2.150&Aring;" /> '''RAB domain of huma...)
Current revision (10:54, 30 August 2023) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2p5s.gif|left|200px]]<br />
 
-
<applet load="2p5s" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2p5s, resolution 2.150&Aring;" />
 
-
'''RAB domain of human RASEF in complex with GDP'''<br />
 
-
==About this Structure==
+
==RAB domain of human RASEF in complex with GDP==
-
2P5S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with GDP and UNX as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2P5S OCA].
+
<StructureSection load='2p5s' size='340' side='right'caption='[[2p5s]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2p5s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P5S FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5s OCA], [https://pdbe.org/2p5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p5s RCSB], [https://www.ebi.ac.uk/pdbsum/2p5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p5s ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RASEF_HUMAN RASEF_HUMAN] Binds predominantly GDP, and also GTP.<ref>PMID:17448446</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p5/2p5s_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p5s ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C.H.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Bochkarev, A.]]
+
[[Category: Bochkarev A]]
-
[[Category: Edwards, A.M.]]
+
[[Category: Edwards AM]]
-
[[Category: Landry, R.]]
+
[[Category: Landry R]]
-
[[Category: Park, H.]]
+
[[Category: Park H]]
-
[[Category: SGC, Structural.Genomics.Consortium.]]
+
[[Category: Shen Y]]
-
[[Category: Shen, Y.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Tempel W]]
-
[[Category: Tempel, W.]]
+
[[Category: Wang J]]
-
[[Category: Wang, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
[[Category: Zhu H]]
-
[[Category: Zhu, H.]]
+
-
[[Category: GDP]]
+
-
[[Category: UNX]]
+
-
[[Category: g-protein]]
+
-
[[Category: gdp]]
+
-
[[Category: rab]]
+
-
[[Category: sgc]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural genomics consortium]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:20:54 2007''
+

Current revision

RAB domain of human RASEF in complex with GDP

PDB ID 2p5s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2p5s"
Personal tools