This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2hw5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:02, 30 August 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2hw5.gif|left|200px]]
 
-
<!--
+
==The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1==
-
The line below this paragraph, containing "STRUCTURE_2hw5", creates the "Structure Box" on the page.
+
<StructureSection load='2hw5' size='340' side='right'caption='[[2hw5]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2hw5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HW5 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_2hw5| PDB=2hw5 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hw5 OCA], [https://pdbe.org/2hw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hw5 RCSB], [https://www.ebi.ac.uk/pdbsum/2hw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hw5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ECHM_HUMAN ECHM_HUMAN] Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hw/2hw5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hw5 ConSurf].
 +
<div style="clear:both"></div>
-
'''The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1'''
+
==See Also==
-
 
+
*[[Enoyl-CoA hydratase 3D structures|Enoyl-CoA hydratase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2HW5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW5 OCA].
+
-
[[Category: Enoyl-CoA hydratase]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Debreczeni, J.]]
+
[[Category: Debreczeni J]]
-
[[Category: Delft, F von.]]
+
[[Category: Edwards A]]
-
[[Category: Edwards, A.]]
+
[[Category: Gileadi O]]
-
[[Category: Gileadi, O.]]
+
[[Category: Gorrec F]]
-
[[Category: Gorrec, F.]]
+
[[Category: Kavanagh K]]
-
[[Category: Kavanagh, K.]]
+
[[Category: Niesen F]]
-
[[Category: Niesen, F.]]
+
[[Category: Oppermann U]]
-
[[Category: Oppermann, U.]]
+
[[Category: Pike ACW]]
-
[[Category: Pike, A C.W.]]
+
[[Category: Salah E]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sundstrom M]]
-
[[Category: Salah, E.]]
+
[[Category: Turnbull AP]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Ugochukwu E]]
-
[[Category: Turnbull, A P.]]
+
[[Category: Umeano C]]
-
[[Category: Ugochukwu, E.]]
+
[[Category: Weigelt J]]
-
[[Category: Umeano, C.]]
+
[[Category: Von Delft F]]
-
[[Category: Weigelt, J.]]
+
-
[[Category: Beta-oxidation]]
+
-
[[Category: Coa]]
+
-
[[Category: Enoyl-coa hydratase]]
+
-
[[Category: Fatty acid metabolism]]
+
-
[[Category: Hydratase/isomerase superfamily]]
+
-
[[Category: Lyase]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:47:04 2008''
+

Current revision

The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1

PDB ID 2hw5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools