2i7q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:07, 30 August 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2i7q.gif|left|200px]]
 
-
<!--
+
==Crystal structure of Human Choline Kinase A==
-
The line below this paragraph, containing "STRUCTURE_2i7q", creates the "Structure Box" on the page.
+
<StructureSection load='2i7q' size='340' side='right'caption='[[2i7q]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2i7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I7Q FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-
{{STRUCTURE_2i7q| PDB=2i7q | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i7q OCA], [https://pdbe.org/2i7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i7q RCSB], [https://www.ebi.ac.uk/pdbsum/2i7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i7q ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i7/2i7q_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i7q ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of Human Choline Kinase A'''
+
==See Also==
-
 
+
*[[Choline kinase 3D structures|Choline kinase 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
2I7Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7Q OCA].
+
__TOC__
-
[[Category: Choline kinase]]
+
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Bochkarev, A.]]
+
[[Category: Bochkarev A]]
-
[[Category: Edwards, A M.]]
+
[[Category: Edwards AM]]
-
[[Category: Landry, R.]]
+
[[Category: Landry R]]
-
[[Category: Nedyalkova, L.]]
+
[[Category: Nedyalkova L]]
-
[[Category: Park, H.]]
+
[[Category: Park H]]
-
[[Category: Rabeh, W M.]]
+
[[Category: Rabeh WM]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Tempel W]]
-
[[Category: Tempel, W.]]
+
[[Category: Wasney G]]
-
[[Category: Wasney, G.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
-
[[Category: Choline kinase]]
+
-
[[Category: Non-protein kinase]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:11:01 2008''
+

Current revision

Crystal structure of Human Choline Kinase A

PDB ID 2i7q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2i7q"
Personal tools